Summary: Counting all k -mers in a given dataset is a standard procedure in many bioinformatics applications. We introduce KMC3, a significant improvement of the former KMC2 algorithm together with KMC tools for manipulating k -mer databases. Usefulness of the tools is shown on a few real problems.
Availability and implementation: Program is freely available at http://sun.aei.polsl.pl/REFRESH/kmc .
Contact: sebastian.deorowicz@polsl.pl.
Supplementary information: Supplementary data are available at Bioinformatics online.
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