Selective impairment of goal-directed decision-making following lesions to the human ventromedial prefrontal cortex

Brain. 2017 Jun 1;140(6):1743-1756. doi: 10.1093/brain/awx105.

Justin Reber^{1

2}, Justin S Feinstein³, John P O'Doherty⁴, Mimi Liljeholm^{4

5}, Ralph Adolphs⁴, Daniel Tranel^{1

2}

¹ Department of Psychological and Brain Sciences, University of Iowa, Iowa, IA, USA.
² Department of Neurology, Division of Neuropsychology and Cognitive Neuroscience, University of Iowa College of Medicine, Iowa, IA, USA.
³ Laureate Institute for Brain Research and Oxley College of Health Sciences, University of Tulsa, Tulsa, OK, USA.
⁴ Division of Humanities and Social Sciences and Computation and Neural Systems Program, California Institute of Technology, Pasadena, CA, USA.
⁵ Department of Cognitive Sciences, University of California, Irvine, CA, USA.

No abstract available

Keywords: decision-making; devaluation; instrumental; reward; vmPFC.

MeSH terms