A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex

Alena Zíková; Zdeněk Verner; Anna Nenarokova; Paul A M Michels; Julius Lukeš

doi:10.1371/journal.ppat.1006679

A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex

PLoS Pathog. 2017 Dec 21;13(12):e1006679. doi: 10.1371/journal.ppat.1006679. eCollection 2017 Dec.

Authors

Alena Zíková^{1

2}, Zdeněk Verner^{1

3}, Anna Nenarokova^{1

2}, Paul A M Michels⁴, Julius Lukeš^{1

2}

Affiliations

¹ Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice, Czech Republic.
² Faculty of Science, University of South Bohemia, České Budějovice, Czech Republic.
³ Faculty of Sciences, Charles University, Prague, Czech Republic.
⁴ Centre for Immunity, Infection and Evolution, The University of Edinburgh, Edinburgh, United Kingdom.

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Humans
Life Cycle Stages / physiology
Mitochondrial Proteins / metabolism*
Proteome / analysis
Proteome / metabolism
Protozoan Proteins / metabolism*
Trypanosoma brucei brucei / growth & development*
Trypanosoma brucei brucei / metabolism*

Substances

Mitochondrial Proteins
Proteome
Protozoan Proteins

Grants and funding

This work was supported by the ERC CZ awards LL1205 and LL1601 and by the Czech Grant Agency awards 17-22248S and 15-21974S to AZ and JL, respectively. ZV was supported by LQ1604 NPU II provided by MEYS. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.