Human entorhinal cortex represents visual space using a boundary-anchored grid

Nat Neurosci. 2018 Feb;21(2):191-194. doi: 10.1038/s41593-017-0049-1. Epub 2018 Jan 8.

Abstract

When participants performed a visual search task, functional MRI responses in entorhinal cortex exhibited a sixfold periodic modulation by gaze-movement direction. The orientation of this modulation was determined by the shape and orientation of the bounded search space. These results indicate that human entorhinal cortex represents visual space using a boundary-anchored grid, analogous to that used by rodents to represent navigable space.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Attention / physiology*
  • Entorhinal Cortex / diagnostic imaging
  • Entorhinal Cortex / physiology*
  • Eye Movements / physiology
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Male
  • Orientation / physiology*
  • Oxygen / blood
  • Photic Stimulation
  • Space Perception / physiology*
  • Spatial Navigation / physiology*
  • Young Adult

Substances

  • Oxygen