Abstract
The distance between the simian virus 40 early promoter elements has been altered by inserting either odd or even multiples of half a DNA turn. There are marked differences in the in vivo effects of these two types of insertions on initiation of transcription from this promoter.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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Chromosome Deletion
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DNA, Viral / genetics
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DNA-Binding Proteins / genetics
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Enhancer Elements, Genetic
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Gene Expression Regulation
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Mutation
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Nucleic Acid Conformation
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Promoter Regions, Genetic*
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Protein Binding
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Simian virus 40 / genetics*
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Transcription Factors / genetics*
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Transcription, Genetic*
Substances
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DNA, Viral
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DNA-Binding Proteins
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Transcription Factors