Terminators of transcription with RNA polymerase from Escherichia coli: what they look like and how to find them

J Biomol Struct Dyn. 1986 Feb;3(4):705-23. doi: 10.1080/07391102.1986.10508457.

Abstract

We present here a compilation of prokaryotic transcription terminator sequences (ref. 1-152). The compilation includes 49 independent terminators, 52 speculated independent terminators, 27 sites shown to function in vivo, and some 20 proven or speculated rho-dependent terminators. In addition to the well-known features of independent terminators (dyad symmetry and T-run), two consensus are found: CGGG(C/G) upstream and TCTG downstream of the termination point. A subset of the collection of sequence has been used to construct a computer algorithm to locate independent terminators by sequence analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Base Sequence
  • DNA-Directed RNA Polymerases
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Genes, Regulator*
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • Terminator Regions, Genetic*
  • Transcription, Genetic*

Substances

  • DNA-Directed RNA Polymerases