CRISPResso2 provides accurate and rapid genome editing sequence analysis

Kendell Clement; Holly Rees; Matthew C Canver; Jason M Gehrke; Rick Farouni; Jonathan Y Hsu; Mitchel A Cole; David R Liu; J Keith Joung; Daniel E Bauer; Luca Pinello

doi:10.1038/s41587-019-0032-3

CRISPResso2 provides accurate and rapid genome editing sequence analysis

Nat Biotechnol. 2019 Mar;37(3):224-226. doi: 10.1038/s41587-019-0032-3.

Authors

Kendell Clement^{1

2

3}, Holly Rees^{4

5

6}, Matthew C Canver^{1

2

3}, Jason M Gehrke^{2

3}, Rick Farouni^{1

2

3}, Jonathan Y Hsu^{1

2

3}, Mitchel A Cole⁷, David R Liu^{4

5

6}, J Keith Joung^{2

3}, Daniel E Bauer^{8

9

10

11}, Luca Pinello^{12

13

14}

Affiliations

¹ Broad Institute of MIT and Harvard, Cambridge, MA, USA.
² Molecular Pathology Unit, Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.
³ Department of Pathology, Harvard Medical School, Boston, MA, USA.
⁴ Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
⁵ Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
⁶ Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
⁷ Division of Hematology/Oncology, Boston Children's Hospital; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
⁸ Broad Institute of MIT and Harvard, Cambridge, MA, USA. daniel.bauer@childrens.harvard.edu.
⁹ Division of Hematology/Oncology, Boston Children's Hospital; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. daniel.bauer@childrens.harvard.edu.
¹⁰ Department of Pediatrics, Harvard Medical School, Boston, MA, USA. daniel.bauer@childrens.harvard.edu.
¹¹ Harvard Stem Cell Institute, Cambridge, MA, USA. daniel.bauer@childrens.harvard.edu.
¹² Broad Institute of MIT and Harvard, Cambridge, MA, USA. lpinello@mgh.harvard.edu.
¹³ Molecular Pathology Unit, Center for Cancer Research and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA. lpinello@mgh.harvard.edu.
¹⁴ Department of Pathology, Harvard Medical School, Boston, MA, USA. lpinello@mgh.harvard.edu.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

CRISPR-Cas Systems / genetics*
Gene Editing*
Genome, Human / genetics*
Humans
Polymorphism, Single Nucleotide / genetics
RNA Editing / genetics
Sequence Analysis

Publication types

MeSH terms

Grants and funding