Abstract
The energization of rho + and rho degrees isolated mitochondria was measured using a tetraphenylphosphonium selective electrode. In both strains translocase mediated ATP/ADP exchange energization was observed. This energization was more sensitive to uncoupler than that induced by respiration in rho + mitochondria. This observation is in accordance with the hypersensitivity of rho - cell growth to uncoupler.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenine Nucleotides / metabolism*
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Adenosine Triphosphate / metabolism
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Biological Transport
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Carbonyl Cyanide m-Chlorophenyl Hydrazone / pharmacology
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Cyanides / pharmacology
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Energy Metabolism*
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Mitochondria / drug effects
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Mitochondria / metabolism*
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Mutation
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Saccharomyces cerevisiae / metabolism*
Substances
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Adenine Nucleotides
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Cyanides
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Carbonyl Cyanide m-Chlorophenyl Hydrazone
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Adenosine Triphosphate