The role of adenine nucleotide translocation in the energization of the inner membrane of mitochondria isolated from rho + and rho degree strains of Saccharomyces cerevisiae

Biochem Biophys Res Commun. 1985 Nov 15;132(3):1116-23. doi: 10.1016/0006-291x(85)91922-9.

Abstract

The energization of rho + and rho degrees isolated mitochondria was measured using a tetraphenylphosphonium selective electrode. In both strains translocase mediated ATP/ADP exchange energization was observed. This energization was more sensitive to uncoupler than that induced by respiration in rho + mitochondria. This observation is in accordance with the hypersensitivity of rho - cell growth to uncoupler.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenine Nucleotides / metabolism*
  • Adenosine Triphosphate / metabolism
  • Biological Transport
  • Carbonyl Cyanide m-Chlorophenyl Hydrazone / pharmacology
  • Cyanides / pharmacology
  • Energy Metabolism*
  • Mitochondria / drug effects
  • Mitochondria / metabolism*
  • Mutation
  • Saccharomyces cerevisiae / metabolism*

Substances

  • Adenine Nucleotides
  • Cyanides
  • Carbonyl Cyanide m-Chlorophenyl Hydrazone
  • Adenosine Triphosphate