The use of sample genealogies for studying a selectively neutral m-loci model with recombination

Theor Popul Biol. 1985 Dec;28(3):382-96. doi: 10.1016/0040-5809(85)90036-x.

Abstract

A selectively neutral m-loci model with recombination is studied. A general method is developed to calculate the variance of the number of segregating sites in samples of arbitrary size and the m-loci homozygosity. The method is based on properties of the genealogy of the sample rather than diffusion approximations. To demonstrate the scope of the method several calculations are presented.

MeSH terms

  • Genetic Variation
  • Genetics, Population
  • Germ Cells
  • Mathematics
  • Models, Genetic
  • Recombination, Genetic*