A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene

Nature. 1984 Dec;312(5995):612-5. doi: 10.1038/312612a0.

Abstract

A bacterial repressor protein blocks transcription of a gene in yeast when its operator is placed in the promoter between the upstream activator sequence and the transcription start point. Putative transcription terminators from yeast installed in the same region of the promoter have a similar effect.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Proteins / metabolism*
  • Base Sequence
  • Escherichia coli / genetics*
  • Genes, Fungal*
  • Genes, Regulator*
  • Operon
  • Plasmids
  • Repressor Proteins / metabolism*
  • Saccharomyces cerevisiae / genetics*
  • Serine Endopeptidases*
  • Terminator Regions, Genetic*
  • Transcription Factors / metabolism*
  • Transcription, Genetic*

Substances

  • Bacterial Proteins
  • LexA protein, Bacteria
  • Repressor Proteins
  • Transcription Factors
  • Serine Endopeptidases