Principles of selective inactivation of viral genome. I. UV-induced inactivation of influenza virus

E I Budowsky; S E Bresler; E A Friedman; N V Zheleznova

doi:10.1007/BF01314577

Principles of selective inactivation of viral genome. I. UV-induced inactivation of influenza virus

Arch Virol. 1981;68(3-4):239-47. doi: 10.1007/BF01314577.

Authors

E I Budowsky, S E Bresler, E A Friedman, N V Zheleznova

PMID: 7271457
DOI: 10.1007/BF01314577

Abstract

Photosensitivity of infectious, haemagglutinating and neuraminidase activities of influenza virus has been determined experimentally. The photosensitivity of infectious activity of type B (strain Hongkong/8/73) influenza virus ws found to be higher than that of type A strains NIB-4 (N3N2-3), Leningrad/399/76 (H3N2-3) and NIB-6 (H1N1). The data obtained may be used for the determination of conditions of UV-irradiation for preparation of UV-inactivated antiviral vaccines.

Publication types

Comparative Study

MeSH terms

Hemagglutination Tests
Neuraminidase / metabolism
Orthomyxoviridae / enzymology
Orthomyxoviridae / pathogenicity
Orthomyxoviridae / radiation effects*
Species Specificity
Ultraviolet Rays

Substances

Neuraminidase