Gene amplification and drug resistance

Sci Am. 1980 Nov;243(5):60-9. doi: 10.1038/scientificamerican1180-60.
No abstract available

MeSH terms

  • Animals
  • Base Sequence
  • Cell Line
  • Chromosomes / metabolism*
  • Cricetinae
  • Cricetulus
  • DNA / biosynthesis*
  • Drug Resistance*
  • Female
  • Gene Amplification / drug effects
  • Methotrexate / pharmacology
  • Ovary
  • Protein Biosynthesis
  • RNA, Messenger / metabolism
  • Transcription, Genetic
  • Translocation, Genetic

Substances

  • RNA, Messenger
  • DNA
  • Methotrexate