Genetic rescue of surface metalloproteinase (gp63)-deficiency in Leishmania amazonensis variants increases their infection of macrophages at the early phase

Mol Biochem Parasitol. 1994 Aug;66(2):345-7. doi: 10.1016/0166-6851(94)90160-0.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Genetic Complementation Test
  • Genetic Variation
  • Genetic Vectors
  • In Vitro Techniques
  • Leishmania / enzymology*
  • Leishmania / genetics
  • Leishmania / pathogenicity
  • Leishmaniasis / etiology
  • Macrophages / parasitology
  • Metalloendopeptidases / deficiency
  • Metalloendopeptidases / genetics*
  • Mice
  • Transfection
  • Virulence / genetics

Substances

  • Metalloendopeptidases
  • glycoprotein gp63, Leishmania