Antigenic peptide binding by class I and class II histocompatibility proteins

Structure. 1994 Apr 15;2(4):245-51. doi: 10.1016/s0969-2126(00)00026-5.

Abstract

The recent determination of the structure of a class II MHC molecule complexed to a specific peptide reveals both similarities and differences with peptide binding by class I MHC.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Antigens / metabolism*
  • Binding Sites
  • Histocompatibility Antigens Class I / chemistry
  • Histocompatibility Antigens Class I / metabolism*
  • Histocompatibility Antigens Class II / chemistry
  • Histocompatibility Antigens Class II / metabolism*
  • Humans
  • Hydrogen Bonding
  • Mice
  • Models, Molecular
  • Molecular Sequence Data
  • Peptide Fragments / metabolism*
  • Protein Binding
  • Protein Conformation*
  • Sequence Alignment

Substances

  • Antigens
  • Histocompatibility Antigens Class I
  • Histocompatibility Antigens Class II
  • Peptide Fragments