Abstract
The effects of regular daily coffee consumption on liver enzymes were studied in a large number of subjects from the general population. In coffee drinkers, liver enzymes (gamma-glutamyl transferase, alanine-amino transferase, and alkaline phosphatase) and serum bilirubin were lower than in non-coffee-drinking subjects or in those consuming less than 3 cups daily. The hypothesis proposed is that liver enzymes are a target for caffeine contained in coffee.
MeSH terms
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Aged
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Alanine Transaminase / blood*
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Alcohol Drinking / adverse effects
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Alkaline Phosphatase / blood*
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Analysis of Variance
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Bilirubin / blood*
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Blood Pressure
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Cardiac Output
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Cardiovascular Diseases / epidemiology
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Cardiovascular Diseases / etiology
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Coffee / adverse effects*
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Echocardiography
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Female
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Humans
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Hypertension / blood*
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Hypertension / complications
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Hypertension / diagnostic imaging
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Hypertension / physiopathology
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Male
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Multivariate Analysis
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Myocardial Contraction*
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Prevalence
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Prospective Studies
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Random Allocation
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Risk Factors
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Stroke Volume
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gamma-Glutamyltransferase / blood*
Substances
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Coffee
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gamma-Glutamyltransferase
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Alanine Transaminase
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Alkaline Phosphatase
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Bilirubin