Abstract
The mukB operon is located at 21 min on the Escherichia coli chromosome and seems to consist of four genes, orf30 (smtA), mukF, mukE, and mukB. Based on sequence similarity, the promoter-proximal gene, orf30 (smtA), could encode an S-adenosylmethionine-dependent methyltransferase. The smtA gene is not essential for cell growth and its expression is positively regulated by H-NS, an Escherichia coli histone-like protein.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Base Sequence
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Cloning, Molecular
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DNA, Bacterial / genetics
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Escherichia coli / enzymology
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Escherichia coli / genetics*
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Methyltransferases / genetics*
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Molecular Sequence Data
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Mutation / genetics
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Promoter Regions, Genetic / genetics
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S-Adenosylmethionine / genetics*
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Sequence Homology, Nucleic Acid
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beta-Galactosidase / metabolism
Substances
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DNA, Bacterial
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S-Adenosylmethionine
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Methyltransferases
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beta-Galactosidase
Associated data
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GENBANK/D17468
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GENBANK/D26440
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GENBANK/J04423
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GENBANK/K01183
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GENBANK/M87509
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GENBANK/X72948
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GENBANK/X81413