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Year Number of Results
2008 2
2010 1
2011 1
2012 1
2013 1
2014 1
2016 4
2017 2
2018 1
2019 4
2020 2
2021 2
2022 5
2023 6
2024 1

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32 results

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Page 1
Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43.
Jiang YX, Cao Q, Sawaya MR, Abskharon R, Ge P, DeTure M, Dickson DW, Fu JY, Ogorzalek Loo RR, Loo JA, Eisenberg DS. Jiang YX, et al. Among authors: abskharon r. Nature. 2022 May;605(7909):304-309. doi: 10.1038/s41586-022-04670-9. Epub 2022 Mar 28. Nature. 2022. PMID: 35344984 Free PMC article.
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CP, Goodness D, Tian R, Grosjean P, Abskharon R, Eisenberg D, Kanaan NM, Gan L, Condello C, Swaney DL, Kampmann M. Samelson AJ, et al. Among authors: abskharon r. bioRxiv [Preprint]. 2023 Jun 26:2023.06.16.545386. doi: 10.1101/2023.06.16.545386. bioRxiv. 2023. PMID: 37398204 Free PMC article. Preprint.
Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Abskharon R, Pan H, Sawaya MR, Seidler PM, Olivares EJ, Chen Y, Murray KA, Zhang J, Lantz C, Bentzel M, Boyer DR, Cascio D, Nguyen BA, Hou K, Cheng X, Pardon E, Williams CK, Nana AL, Vinters HV, Spina S, Grinberg LT, Seeley WW, Steyaert J, Glabe CG, Ogorzalek Loo RR, Loo JA, Eisenberg DS. Abskharon R, et al. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2300258120. doi: 10.1073/pnas.2300258120. Epub 2023 Oct 6. Proc Natl Acad Sci U S A. 2023. PMID: 37801475 Free PMC article.
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: abskharon r. Nat Commun. 2023 Apr 25;14(1):2379. doi: 10.1038/s41467-023-37865-3. Nat Commun. 2023. PMID: 37185252 Free PMC article.
Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
Murray KA, Hu CJ, Pan H, Lu J, Abskharon R, Bowler JT, Rosenberg GM, Williams CK, Elezi G, Balbirnie M, Faull KF, Vinters HV, Seidler PM, Eisenberg DS. Murray KA, et al. Among authors: abskharon r. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2217835120. doi: 10.1073/pnas.2217835120. Epub 2023 Feb 9. Proc Natl Acad Sci U S A. 2023. PMID: 36757890 Free PMC article.
Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Tayeb-Fligelman E, Cheng X, Tai C, Bowler JT, Griner S, Sawaya MR, Seidler PM, Jiang YX, Lu J, Rosenberg GM, Salwinski L, Abskharon R, Zee CT, Hou K, Li Y, Boyer DR, Murray KA, Falcon G, Anderson DH, Cascio D, Saelices L, Damoiseaux R, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: abskharon r. bioRxiv [Preprint]. 2021 Mar 18:2021.03.05.434000. doi: 10.1101/2021.03.05.434000. bioRxiv. 2021. PMID: 33688654 Free PMC article. Preprint.
De novo designed protein inhibitors of amyloid aggregation and seeding.
Murray KA, Hu CJ, Griner SL, Pan H, Bowler JT, Abskharon R, Rosenberg GM, Cheng X, Seidler PM, Eisenberg DS. Murray KA, et al. Among authors: abskharon r. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206240119. doi: 10.1073/pnas.2206240119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969734 Free PMC article.
32 results