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Page 1
Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer.
J Med Chem. 2023 Apr 27;66(8):5981-6001. doi: 10.1021/acs.jmedchem.3c00276. Epub 2023 Apr 7.
J Med Chem. 2023.
PMID: 37026468
Free PMC article.
Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.
Jahid S, Ortega JA, Vuong LM, Acquistapace IM, Hachey SJ, Flesher JL, La Serra MA, Brindani N, La Sala G, Manigrasso J, Arencibia JM, Bertozzi SM, Summa M, Bertorelli R, Armirotti A, Jin R, Liu Z, Chen CF, Edwards R, Hughes CCW, De Vivo M, Ganesan AK.
Jahid S, et al. Among authors: acquistapace im.
Cell Rep. 2022 Apr 5;39(1):110641. doi: 10.1016/j.celrep.2022.110641.
Cell Rep. 2022.
PMID: 35385746
Free PMC article.
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Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Acquistapace IM, Thompson EJ, Kühn I, Bedford MR, Brearley CA, Hemmings AM.
Acquistapace IM, et al.
Int J Mol Sci. 2022 Jun 6;23(11):6346. doi: 10.3390/ijms23116346.
Int J Mol Sci. 2022.
PMID: 35683026
Free PMC article.
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Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.
Jahid S, Ortega JA, Vuong LM, Acquistapace IM, Hachey SJ, Flesher JL, La Serra MA, Brindani N, La Sala G, Manigrasso J, Arencibia JM, Bertozzi SM, Summa M, Bertorelli R, Armirotti A, Jin R, Liu Z, Chen CF, Edwards R, Hughes CCW, De Vivo M, Ganesan AK.
Jahid S, et al. Among authors: acquistapace im.
Cell Rep. 2022 Apr 26;39(4):110760. doi: 10.1016/j.celrep.2022.110760.
Cell Rep. 2022.
PMID: 35476990
Free PMC article.
No abstract available.
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Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism.
Acquistapace IM, Zi Etek MA, Li AWH, Salmon M, Kühn I, Bedford MR, Brearley CA, Hemmings AM.
Acquistapace IM, et al.
J Biol Chem. 2020 Dec 18;295(51):17724-17737. doi: 10.1074/jbc.RA120.015925.
J Biol Chem. 2020.
PMID: 33454010
Free PMC article.
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