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Safety and efficacy of sargramostim (GM-CSF) in the treatment of Alzheimer's disease.
Potter H, Woodcock JH, Boyd TD, Coughlan CM, O'Shaughnessy JR, Borges MT, Thaker AA, Raj BA, Adamszuk K, Scott D, Adame V, Anton P, Chial HJ, Gray H, Daniels J, Stocker ME, Sillau SH. Potter H, et al. Among authors: adame v. Alzheimers Dement (N Y). 2021 Mar 24;7(1):e12158. doi: 10.1002/trc2.12158. eCollection 2021. Alzheimers Dement (N Y). 2021. PMID: 33778150 Free PMC article.
The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice.
Ahmed MM, Wang AC, Elos M, Chial HJ, Sillau S, Solano DA, Coughlan C, Aghili L, Anton P, Markham N, Adame V, Gardiner KJ, Boyd TD, Potter H. Ahmed MM, et al. Among authors: adame v. Neurobiol Dis. 2022 Jun 15;168:105694. doi: 10.1016/j.nbd.2022.105694. Epub 2022 Mar 18. Neurobiol Dis. 2022. PMID: 35307513 Free PMC article.
Astrogliosis and episodic memory in late life: higher GFAP is related to worse memory and white matter microstructure in healthy aging and Alzheimer's disease.
Bettcher BM, Olson KE, Carlson NE, McConnell BV, Boyd T, Adame V, Solano DA, Anton P, Markham N, Thaker AA, Jensen AM, Dallmann EN, Potter H, Coughlan C. Bettcher BM, et al. Among authors: adame v. Neurobiol Aging. 2021 Jul;103:68-77. doi: 10.1016/j.neurobiolaging.2021.02.012. Epub 2021 Feb 26. Neurobiol Aging. 2021. PMID: 33845398 Free PMC article.