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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2000 1
2002 2
2003 2
2004 4
2006 1
2007 1
2008 5
2010 4
2011 5
2012 3
2013 2
2015 2
2016 2
2017 1
2018 3
2019 3
2020 3
2021 2
2022 4
2023 6
2024 3

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52 results

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Page 1
VCP/p97 regulates Beclin-1-dependent autophagy initiation.
Hill SM, Wrobel L, Ashkenazi A, Fernandez-Estevez M, Tan K, Bürli RW, Rubinsztein DC. Hill SM, et al. Among authors: burli rw. Nat Chem Biol. 2021 Apr;17(4):448-455. doi: 10.1038/s41589-020-00726-x. Epub 2021 Jan 28. Nat Chem Biol. 2021. PMID: 33510452
Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction.
Schneeberger M, Brice NL, Pellegrino K, Parolari L, Shaked JT, Page KJ, Marchildon F, Barrows DW, Carroll TS, Topilko T, Mulligan VM, Newman R, Doyle K, Bürli R, Barker DF, Glen A, Ortuño MJ, Nectow AR, Renier N, Cohen P, Carlton M, Heintz N, Friedman JM. Schneeberger M, et al. Among authors: burli r. Nat Metab. 2022 Nov;4(11):1495-1513. doi: 10.1038/s42255-022-00677-8. Epub 2022 Nov 21. Nat Metab. 2022. PMID: 36411386 Free PMC article.
Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice.
Jarvis R, Josephine Ng SF, Nathanson AJ, Cardarelli RA, Abiraman K, Wade F, Evans-Strong A, Fernandez-Campa MP, Deeb TZ, Smalley JL, Jamier T, Gurrell IK, McWilliams L, Kawatkar A, Conway LC, Wang Q, Burli RW, Brandon NJ, Chessell IP, Goldman AJ, Maguire JL, Moss SJ. Jarvis R, et al. Among authors: burli rw. Cell Rep Med. 2023 Mar 21;4(3):100957. doi: 10.1016/j.xcrm.2023.100957. Epub 2023 Mar 7. Cell Rep Med. 2023. PMID: 36889319 Free PMC article.
Discovery and Characterization of Novel CNS-Penetrant GPR55 Agonists.
Hewer RC, Christie LA, Doyle KJ, Xu X, Roberts MJ, Dickson L, Cheung T, Cadwalladr DH, Pickford P, Teall M, Powell JAC, Sheardown S, Narayana L, Brice NL, Dawson LA, Carlton M, Bürli RW. Hewer RC, et al. Among authors: burli rw. J Med Chem. 2023 Sep 28;66(18):12858-12876. doi: 10.1021/acs.jmedchem.3c00784. Epub 2023 Sep 14. J Med Chem. 2023. PMID: 37708305
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.
Wrobel L, Hill SM, Djajadikerta A, Fernandez-Estevez M, Karabiyik C, Ashkenazi A, Barratt VJ, Stamatakou E, Gunnarsson A, Rasmusson T, Miele EW, Beaton N, Bruderer R, Feng Y, Reiter L, Castaldi MP, Jarvis R, Tan K, Bürli RW, Rubinsztein DC. Wrobel L, et al. Among authors: burli rw. Nat Commun. 2022 Jul 16;13(1):4146. doi: 10.1038/s41467-022-31905-0. Nat Commun. 2022. PMID: 35842429 Free PMC article.
Sequence-specific DNA recognition by polyamides.
Dervan PB, Bürli RW. Dervan PB, et al. Among authors: burli rw. Curr Opin Chem Biol. 1999 Dec;3(6):688-93. doi: 10.1016/s1367-5931(99)00027-7. Curr Opin Chem Biol. 1999. PMID: 10600731 Review.
Characterisation of C101248: A novel selective THIK-1 channel inhibitor for the modulation of microglial NLRP3-inflammasome.
Ossola B, Rifat A, Rowland A, Hunter H, Drinkall S, Bender C, Hamlischer M, Teall M, Burley R, Barker DF, Cadwalladr D, Dickson L, Lawrence JMK, Harvey JRM, Lizio M, Xu X, Kavanagh E, Cheung T, Sheardown S, Lawrence CB, Harte M, Brough D, Madry C, Matthews K, Doyle K, Page K, Powell J, Brice NL, Bürli RW, Carlton MB, Dawson LA. Ossola B, et al. Among authors: burli rw. Neuropharmacology. 2023 Feb 15;224:109330. doi: 10.1016/j.neuropharm.2022.109330. Epub 2022 Nov 12. Neuropharmacology. 2023. PMID: 36375694 Free PMC article.
Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity.
Johansson P, Kaspersson K, Gurrell IK, Bäck E, Eketjäll S, Scott CW, Cebers G, Thorne P, McKenzie MJ, Beaton H, Davey P, Kolmodin K, Holenz J, Duggan ME, Budd Haeberlein S, Bürli RW. Johansson P, et al. Among authors: burli rw. J Med Chem. 2018 Apr 26;61(8):3491-3502. doi: 10.1021/acs.jmedchem.7b01716. Epub 2018 Apr 10. J Med Chem. 2018. PMID: 29617572
52 results