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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2004 1
2006 1
2007 1
2008 2
2009 2
2010 1
2011 3
2012 4
2013 4
2014 1
2015 2
2016 3
2017 1
2018 2
2019 3
2020 3
2021 2
2022 1
2023 4
2024 1

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40 results

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Page 1
Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
Angst D, Gessier F, Janser P, Vulpetti A, Wälchli R, Beerli C, Littlewood-Evans A, Dawson J, Nuesslein-Hildesheim B, Wieczorek G, Gutmann S, Scheufler C, Hinniger A, Zimmerlin A, Funhoff EG, Pulz R, Cenni B. Angst D, et al. Among authors: beerli c. J Med Chem. 2020 May 28;63(10):5102-5118. doi: 10.1021/acs.jmedchem.9b01916. Epub 2020 Mar 4. J Med Chem. 2020. PMID: 32083858
Increased Remyelination and Proregenerative Microglia Under Siponimod Therapy in Mechanistic Models.
Dietrich M, Hecker C, Martin E, Langui D, Gliem M, Stankoff B, Lubetzki C, Gruchot J, Göttle P, Issberner A, Nasiri M, Ramseier P, Beerli C, Tisserand S, Beckmann N, Shimshek D, Petzsch P, Akbar D, Levkau B, Stark H, Köhrer K, Hartung HP, Küry P, Meuth SG, Bigaud M, Zalc B, Albrecht P. Dietrich M, et al. Among authors: beerli c. Neurol Neuroimmunol Neuroinflamm. 2022 Mar 30;9(3):e1161. doi: 10.1212/NXI.0000000000001161. Print 2022 May. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 35354603 Free PMC article.
Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase.
Markert C, Thoma G, Srinivas H, Bollbuck B, Lüönd RM, Miltz W, Wälchli R, Wolf R, Hinrichs J, Bergsdorf C, Azzaoui K, Penno CA, Klein K, Wack N, Jäger P, Hasler F, Beerli C, Loetscher P, Dawson J, Wieczorek G, Numao S, Littlewood-Evans A, Röhn TA. Markert C, et al. Among authors: beerli c. J Med Chem. 2021 Feb 25;64(4):1889-1903. doi: 10.1021/acs.jmedchem.0c01955. Epub 2021 Feb 16. J Med Chem. 2021. PMID: 33592148
Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase.
Thoma G, Markert C, Lueoend R, Miltz W, Spanka C, Bollbuck B, Wolf RM, Srinivas H, Penno CA, Kiffe M, Gajewska M, Bednarczyk D, Wieczorek G, Evans A, Beerli C, Röhn TA. Thoma G, et al. Among authors: beerli c. J Med Chem. 2023 Dec 14;66(23):16410-16425. doi: 10.1021/acs.jmedchem.3c01866. Epub 2023 Nov 28. J Med Chem. 2023. PMID: 38015154
Orally bioavailable competitive CCR5 antagonists.
Thoma G, Nuninger F, Schaefer M, Akyel KG, Albert R, Beerli C, Bruns C, Francotte E, Luyten M, MacKenzie D, Oberer L, Streiff MB, Wagner T, Walter H, Weckbecker G, Zerwes HG. Thoma G, et al. Among authors: beerli c. J Med Chem. 2004 Apr 8;47(8):1939-55. doi: 10.1021/jm031046g. J Med Chem. 2004. PMID: 15055994
Inertial picobalance reveals fast mass fluctuations in mammalian cells.
Martínez-Martín D, Fläschner G, Gaub B, Martin S, Newton R, Beerli C, Mercer J, Gerber C, Müller DJ. Martínez-Martín D, et al. Among authors: beerli c. Nature. 2017 Oct 25;550(7677):500-505. doi: 10.1038/nature24288. Nature. 2017. PMID: 29072271
40 results