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The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics.
Giblin W, Bringman-Rodenbarger L, Guo AH, Kumar S, Monovich AC, Mostafa AM, Skinner ME, Azar M, Mady AS, Chung CH, Kadambi N, Melong KA, Lee HJ, Zhang L, Sajjakulnukit P, Trefely S, Varner EL, Iyer S, Wang M, Wilmott JS, Soyer HP, Sturm RA, Pritchard AL, Andea AA, Scolyer RA, Stark MS, Scott DA, Fullen DR, Bosenberg MW, Chandrasekaran S, Nikolovska-Coleska Z, Verhaegen ME, Snyder NW, Rivera MN, Osterman AL, Lyssiotis CA, Lombard DB. Giblin W, et al. Among authors: bringman rodenbarger l. J Clin Invest. 2021 Jun 15;131(12):e138926. doi: 10.1172/JCI138926. J Clin Invest. 2021. PMID: 33945506 Free PMC article.
Emerging Roles for SIRT5 in Metabolism and Cancer.
Bringman-Rodenbarger LR, Guo AH, Lyssiotis CA, Lombard DB. Bringman-Rodenbarger LR, et al. Antioxid Redox Signal. 2018 Mar 10;28(8):677-690. doi: 10.1089/ars.2017.7264. Epub 2017 Oct 26. Antioxid Redox Signal. 2018. PMID: 28707979 Free PMC article.