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Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis.
Jiang Z, Zhao M, Voilquin L, Jung Y, Aikio MA, Sahai T, Dou FY, Roche AM, Carcamo-Orive I, Knowles JW, Wabitsch M, Appel EA, Maikawa CL, Camporez JP, Shulman GI, Tsai L, Rosen ED, Gardner CD, Spiegelman BM, Svensson KJ. Jiang Z, et al. Among authors: carcamo orive i. Cell Metab. 2021 Sep 7;33(9):1836-1852.e11. doi: 10.1016/j.cmet.2021.07.010. Epub 2021 Aug 3. Cell Metab. 2021. PMID: 34348115 Free PMC article.
A single-cell CRISPRi platform for characterizing candidate genes relevant to metabolic disorders in human adipocytes.
Bielczyk-Maczynska E, Sharma D, Blencowe M, Saliba Gustafsson P, Gloudemans MJ, Yang X, Carcamo-Orive I, Wabitsch M, Svensson KJ, Park CY, Quertermous T, Knowles JW, Li J. Bielczyk-Maczynska E, et al. Among authors: carcamo orive i. Am J Physiol Cell Physiol. 2023 Sep 1;325(3):C648-C660. doi: 10.1152/ajpcell.00148.2023. Epub 2023 Jul 24. Am J Physiol Cell Physiol. 2023. PMID: 37486064 Free article.
FAM13A affects body fat distribution and adipocyte function.
Fathzadeh M, Li J, Rao A, Cook N, Chennamsetty I, Seldin M, Zhou X, Sangwung P, Gloudemans MJ, Keller M, Attie A, Yang J, Wabitsch M, Carcamo-Orive I, Tada Y, Lusis AJ, Shin MK, Molony CM, McLaughlin T, Reaven G, Montgomery SB, Reilly D, Quertermous T, Ingelsson E, Knowles JW. Fathzadeh M, et al. Among authors: carcamo orive i. Nat Commun. 2020 Mar 19;11(1):1465. doi: 10.1038/s41467-020-15291-z. Nat Commun. 2020. PMID: 32193374 Free PMC article.
Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD.
Schnurr TM, Katz SF, Justesen JM, O'Sullivan JW, Saliba-Gustafsson P, Assimes TL, Carcamo-Orive I, Ahmed A, Ashley EA, Hansen T, Knowles JW. Schnurr TM, et al. Among authors: carcamo orive i. Hepatol Commun. 2022 Jul;6(7):1516-1526. doi: 10.1002/hep4.1932. Epub 2022 Mar 15. Hepatol Commun. 2022. PMID: 35293152 Free PMC article.
Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics.
Bonder MJ, Smail C, Gloudemans MJ, Frésard L, Jakubosky D, D'Antonio M, Li X, Ferraro NM, Carcamo-Orive I, Mirauta B, Seaton DD, Cai N, Vakili D, Horta D, Zhao C, Zastrow DB, Bonner DE; HipSci Consortium; iPSCORE consortium; Undiagnosed Diseases Network; PhLiPS consortium; Wheeler MT, Kilpinen H, Knowles JW, Smith EN, Frazer KA, Montgomery SB, Stegle O. Bonder MJ, et al. Among authors: carcamo orive i. Nat Genet. 2021 Mar;53(3):313-321. doi: 10.1038/s41588-021-00800-7. Epub 2021 Mar 4. Nat Genet. 2021. PMID: 33664507 Free PMC article.
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.
Carcamo-Orive I, Hoffman GE, Cundiff P, Beckmann ND, D'Souza SL, Knowles JW, Patel A, Hendry C, Papatsenko D, Abbasi F, Reaven GM, Whalen S, Lee P, Shahbazi M, Henrion MYR, Zhu K, Wang S, Roussos P, Schadt EE, Pandey G, Chang R, Quertermous T, Lemischka I. Carcamo-Orive I, et al. Cell Stem Cell. 2022 Oct 6;29(10):1505. doi: 10.1016/j.stem.2022.08.011. Cell Stem Cell. 2022. PMID: 36206733 Free article. No abstract available.
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