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NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis.
Redox Biol. 2019 May;23:101107. doi: 10.1016/j.redox.2019.101107. Epub 2019 Jan 11.
Redox Biol. 2019.
PMID: 30692038
Free PMC article.
Review.
Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan.
Castro-Portuguez R, Sutphin GL.
Castro-Portuguez R, et al.
Exp Gerontol. 2020 Apr;132:110841. doi: 10.1016/j.exger.2020.110841. Epub 2020 Jan 16.
Exp Gerontol. 2020.
PMID: 31954874
Free PMC article.
Review.
Item in Clipboard
On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging.
Dang H, Castro-Portuguez R, Espejo L, Backer G, Freitas S, Spence E, Meyers J, Shuck K, Gardea EA, Chang LM, Balsa J, Thorns N, Corban C, Liu T, Bean S, Sheehan S, Korstanje R, Sutphin GL.
Dang H, et al. Among authors: castro portuguez r.
Nat Commun. 2023 Dec 14;14(1):8338. doi: 10.1038/s41467-023-43527-1.
Nat Commun. 2023.
PMID: 38097593
Free PMC article.
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Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.
Watson AW, Grant AD, Parker SS, Hill S, Whalen MB, Chakrabarti J, Harman MW, Roman MR, Forte BL, Gowan CC, Castro-Portuguez R, Stolze LK, Franck C, Cusanovich DA, Zavros Y, Padi M, Romanoski CE, Mouneimne G.
Watson AW, et al. Among authors: castro portuguez r.
Cell Rep. 2021 Jun 29;35(13):109293. doi: 10.1016/j.celrep.2021.109293.
Cell Rep. 2021.
PMID: 34192535
Free PMC article.
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Low-level arsenic causes proteotoxic stress and not oxidative stress.
Dodson M, de la Vega MR, Harder B, Castro-Portuguez R, Rodrigues SD, Wong PK, Chapman E, Zhang DD.
Dodson M, et al. Among authors: castro portuguez r.
Toxicol Appl Pharmacol. 2018 Feb 15;341:106-113. doi: 10.1016/j.taap.2018.01.014. Epub 2018 Feb 3.
Toxicol Appl Pharmacol. 2018.
PMID: 29408041
Free PMC article.
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The Emerging Role of 3-Hydroxyanthranilic Acid on C. elegans Aging Immune Function.
Espejo LS, DeNicola D, Chang LM, Hofschneider V, Haskins AE, Balsa J, Freitas SS, Antenor A, Hamming S, Hull B, Castro-Portuguez R, Dang H, Sutphin GL.
Espejo LS, et al. Among authors: castro portuguez r.
bioRxiv [Preprint]. 2024 Jan 9:2024.01.07.574394. doi: 10.1101/2024.01.07.574394.
bioRxiv. 2024.
PMID: 38260592
Free PMC article.
Preprint.
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