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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1999 1
2000 2
2004 1
2005 1
2006 3
2007 4
2008 4
2009 1
2010 1
2011 5
2012 4
2013 2
2014 3
2015 1
2018 1
2019 3
2020 3
2021 2
2022 1
2024 0

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38 results

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Page 1
Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
Chana CK, Maisonneuve P, Posternak G, Grinberg NGA, Poirson J, Ona SM, Ceccarelli DF, Mader P, St-Cyr DJ, Pau V, Kurinov I, Tang X, Deng D, Cui W, Su W, Kuai L, Soll R, Tyers M, Röst HL, Batey RA, Taipale M, Gingras AC, Sicheri F. Chana CK, et al. Among authors: ceccarelli df. J Med Chem. 2022 Oct 13;65(19):12725-12746. doi: 10.1021/acs.jmedchem.2c00509. Epub 2022 Sep 18. J Med Chem. 2022. PMID: 36117290 Free PMC article.
I Siah substrate!
Briant DJ, Ceccarelli DF, Sicheri F. Briant DJ, et al. Among authors: ceccarelli df. Structure. 2006 Apr;14(4):627-8. doi: 10.1016/j.str.2006.03.003. Structure. 2006. PMID: 16615900 Free article.
Functional characterization of a PROTAC directed against BRAF mutant V600E.
Posternak G, Tang X, Maisonneuve P, Jin T, Lavoie H, Daou S, Orlicky S, Goullet de Rugy T, Caldwell L, Chan K, Aman A, Prakesch M, Poda G, Mader P, Wong C, Maier S, Kitaygorodsky J, Larsen B, Colwill K, Yin Z, Ceccarelli DF, Batey RA, Taipale M, Kurinov I, Uehling D, Wrana J, Durocher D, Gingras AC, Al-Awar R, Therrien M, Sicheri F. Posternak G, et al. Among authors: ceccarelli df. Nat Chem Biol. 2020 Nov;16(11):1170-1178. doi: 10.1038/s41589-020-0609-7. Epub 2020 Aug 10. Nat Chem Biol. 2020. PMID: 32778845 Free PMC article.
A substrate binding model for the KEOPS tRNA modifying complex.
Beenstock J, Ona SM, Porat J, Orlicky S, Wan LCK, Ceccarelli DF, Maisonneuve P, Szilard RK, Yin Z, Setiaputra D, Mao DYL, Khan M, Raval S, Schriemer DC, Bayfield MA, Durocher D, Sicheri F. Beenstock J, et al. Among authors: ceccarelli df. Nat Commun. 2020 Dec 4;11(1):6233. doi: 10.1038/s41467-020-19990-5. Nat Commun. 2020. PMID: 33277478 Free PMC article.
Bipartite binding of the N terminus of Skp2 to cyclin A.
Kelso S, Orlicky S, Beenstock J, Ceccarelli DF, Kurinov I, Gish G, Sicheri F. Kelso S, et al. Among authors: ceccarelli df. Structure. 2021 Sep 2;29(9):975-988.e5. doi: 10.1016/j.str.2021.04.011. Epub 2021 May 13. Structure. 2021. PMID: 33989513 Free PMC article.
Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
Teyra J, Singer AU, Schmitges FW, Jaynes P, Kit Leng Lui S, Polyak MJ, Fodil N, Krieger JR, Tong J, Schwerdtfeger C, Brasher BB, Ceccarelli DFJ, Moffat J, Sicheri F, Moran MF, Gros P, Eichhorn PJA, Lenter M, Boehmelt G, Sidhu SS. Teyra J, et al. Among authors: ceccarelli dfj. Structure. 2019 Apr 2;27(4):590-605.e5. doi: 10.1016/j.str.2019.01.002. Epub 2019 Jan 31. Structure. 2019. PMID: 30713027 Free article.
Grb-ing hold of insulin signaling.
Ceccarelli DF, Sicheri F. Ceccarelli DF, et al. Nat Struct Mol Biol. 2009 Aug;16(8):803-4. doi: 10.1038/nsmb0809-803. Nat Struct Mol Biol. 2009. PMID: 19654617 No abstract available.
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Rivkin E, Almeida SM, Ceccarelli DF, Juang YC, MacLean TA, Srikumar T, Huang H, Dunham WH, Fukumura R, Xie G, Gondo Y, Raught B, Gingras AC, Sicheri F, Cordes SP. Rivkin E, et al. Among authors: ceccarelli df. Nature. 2013 Jun 20;498(7454):318-24. doi: 10.1038/nature12296. Epub 2013 May 24. Nature. 2013. PMID: 23708998 Free PMC article.
Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex.
St-Cyr D, Ceccarelli DF, Orlicky S, van der Sloot AM, Tang X, Kelso S, Moore S, James C, Posternak G, Coulombe-Huntington J, Bertomeu T, Marinier A, Sicheri F, Tyers M. St-Cyr D, et al. Among authors: ceccarelli df. Sci Adv. 2021 Oct 29;7(44):eabi5797. doi: 10.1126/sciadv.abi5797. Epub 2021 Oct 27. Sci Adv. 2021. PMID: 34705497 Free PMC article.
38 results