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Page 1
Synthesis of benzopyran derivatives as PPARα and/or PPARγ activators.
Bioorg Med Chem. 2019 Dec 15;27(24):115162. doi: 10.1016/j.bmc.2019.115162. Epub 2019 Oct 30.
Bioorg Med Chem. 2019.
PMID: 31703893
New antitumoral acetogenin 'Guanacone type' derivatives: isolation and bioactivity. Molecular dynamics simulation of diacetyl-guanacone.
Barrachina I, Royo I, Baldoni HA, Chahboune N, Suvire F, DePedro N, Zafra-Polo MC, Bermejo A, El Aouad N, Cabedo N, Saez J, Tormo JR, Enriz RD, Cortes D.
Barrachina I, et al. Among authors: chahboune n.
Bioorg Med Chem. 2007 Jul 1;15(13):4369-81. doi: 10.1016/j.bmc.2007.04.039. Epub 2007 Apr 25.
Bioorg Med Chem. 2007.
PMID: 17482824
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Guanaconetins, new antitumoral acetogenins, mitochondrial complex I and tumor cell growth inhibitors.
Chahboune N, Barrachina I, Royo I, Romero V, Sáez J, Tormo JR, De Pedro N, Estornell E, Zafra-Polo MC, Peláez F, Cortes D.
Chahboune N, et al.
Bioorg Med Chem. 2006 Feb 15;14(4):1089-94. doi: 10.1016/j.bmc.2005.09.036. Epub 2005 Oct 18.
Bioorg Med Chem. 2006.
PMID: 16242335
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Tucumanin, a beta-hydroxy-gamma-lactone bistetrahydrofuranic acetogenin from Annona cherimolia, is a potent inhibitor of mitochondrial complex I.
Barrachina I, Neske A, Granell S, Bermejo A, Chahboune N, El Aouad N, Alvarez O, Bardon A, Zafra-Polo MC.
Barrachina I, et al. Among authors: chahboune n.
Planta Med. 2004 Sep;70(9):866-8. doi: 10.1055/s-2004-827237.
Planta Med. 2004.
PMID: 15503356
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Tucupentol, a novel mono-tetrahydrofuranic acetogenin from Annona montana, as a potent inhibitor of mitochondrial complex I.
Alvarez Colom O, Neske A, Chahboune N, Zafra-Polo MC, Bardón A.
Alvarez Colom O, et al. Among authors: chahboune n.
Chem Biodivers. 2009 Mar;6(3):335-40. doi: 10.1002/cbdv.200800102.
Chem Biodivers. 2009.
PMID: 19319860
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Heterocyclic analogues of squamocin as inhibitors of mitochondrial complex I. On the role of the terminal lactone of annonaceous acetogenins.
Duval RA, Lewin G, Peris E, Chahboune N, Garofano A, Dröse S, Cortes D, Brandt U, Hocquemiller R.
Duval RA, et al. Among authors: chahboune n.
Biochemistry. 2006 Feb 28;45(8):2721-8. doi: 10.1021/bi051261u.
Biochemistry. 2006.
PMID: 16489765
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