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The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.
Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner JUG, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho CFF, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen HC, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M. Wenzel J, et al. Among authors: coelho cff. Nat Neurosci. 2021 Nov;24(11):1522-1533. doi: 10.1038/s41593-021-00926-1. Epub 2021 Oct 21. Nat Neurosci. 2021. PMID: 34675436 Free PMC article.
Syzygium cumini Leaf Extract Reverts Hypertriglyceridemia via Downregulation of the Hepatic XBP-1s/PDI/MTP Axis in Monosodium L-Glutamate-Induced Obese Rats.
França LM, Coêlho CFF, Freitas LNC, Souza ILS, Chagas VT, Debbas V, de Lima TM, de Souza HP, Laurindo FRM, Paes AMA. França LM, et al. Among authors: coelho cff. Oxid Med Cell Longev. 2019 Mar 21;2019:9417498. doi: 10.1155/2019/9417498. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31015892 Free PMC article.
Long-term exposure to high-sucrose diet down-regulates hepatic endoplasmic reticulum-stress adaptive pathways and potentiates de novo lipogenesis in weaned male mice.
Flister KFT, Pinto BAS, França LM, Coêlho CFF, Dos Santos PC, Vale CC, Kajihara D, Debbas V, Laurindo FRM, Paes AMA. Flister KFT, et al. Among authors: coelho cff. J Nutr Biochem. 2018 Dec;62:155-166. doi: 10.1016/j.jnutbio.2018.09.007. Epub 2018 Sep 19. J Nutr Biochem. 2018. PMID: 30300835
14 results