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CELLULAR RNA INTERACTS WITH MAVS TO PROMOTE ANTIVIRAL SIGNALING.
Gokhale NS, Somfleth K, Thompson MG, Sam RK, Marciniak DM, Chu LH, Park M, Dvorkin S, Oberst A, Horner SM, Ong SE, Gale M Jr, Savan R. Gokhale NS, et al. Among authors: dvorkin s. bioRxiv [Preprint]. 2023 Sep 25:2023.09.25.559083. doi: 10.1101/2023.09.25.559083. bioRxiv. 2023. PMID: 37808873 Free PMC article. Preprint.
Encoding canonical DNA quadruplex structure.
Dvorkin SA, Karsisiotis AI, Webba da Silva M. Dvorkin SA, et al. Sci Adv. 2018 Aug 31;4(8):eaat3007. doi: 10.1126/sciadv.aat3007. eCollection 2018 Aug. Sci Adv. 2018. PMID: 30182059 Free PMC article.
CDB-a database for protein heterodimeric complexes.
Aker M, Ohanona S, Fisher S, Katsman E, Dvorkin S, Kopelowitz E, Goldstein M, Barnett-Itzhaki Z, Amitay M. Aker M, et al. Among authors: dvorkin s. Protein Eng Des Sel. 2018 Oct 1;31(10):361-365. doi: 10.1093/protein/gzy030. Protein Eng Des Sel. 2018. PMID: 30452718
Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.
Osipiuk J, Azizi SA, Dvorkin S, Endres M, Jedrzejczak R, Jones KA, Kang S, Kathayat RS, Kim Y, Lisnyak VG, Maki SL, Nicolaescu V, Taylor CA, Tesar C, Zhang YA, Zhou Z, Randall G, Michalska K, Snyder SA, Dickinson BC, Joachimiak A. Osipiuk J, et al. Among authors: dvorkin s. Nat Commun. 2021 Feb 2;12(1):743. doi: 10.1038/s41467-021-21060-3. Nat Commun. 2021. PMID: 33531496 Free PMC article.
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
Drayman N, DeMarco JK, Jones KA, Azizi SA, Froggatt HM, Tan K, Maltseva NI, Chen S, Nicolaescu V, Dvorkin S, Furlong K, Kathayat RS, Firpo MR, Mastrodomenico V, Bruce EA, Schmidt MM, Jedrzejczak R, Muñoz-Alía MÁ, Schuster B, Nair V, Han KY, O'Brien A, Tomatsidou A, Meyer B, Vignuzzi M, Missiakas D, Botten JW, Brooke CB, Lee H, Baker SC, Mounce BC, Heaton NS, Severson WE, Palmer KE, Dickinson BC, Joachimiak A, Randall G, Tay S. Drayman N, et al. Among authors: dvorkin s. Science. 2021 Aug 20;373(6557):931-936. doi: 10.1126/science.abg5827. Epub 2021 Jul 20. Science. 2021. PMID: 34285133 Free PMC article.
Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.
O'Dowd CR, Helm MD, Rountree JSS, Flasz JT, Arkoudis E, Miel H, Hewitt PR, Jordan L, Barker O, Hughes C, Rozycka E, Cassidy E, McClelland K, Odrzywol E, Page N, Feutren-Burton S, Dvorkin S, Gavory G, Harrison T. O'Dowd CR, et al. Among authors: dvorkin s. ACS Med Chem Lett. 2018 Feb 21;9(3):238-243. doi: 10.1021/acsmedchemlett.7b00512. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541367 Free PMC article.
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