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TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome.
Olsen RHJ, DiBerto JF, English JG, Glaudin AM, Krumm BE, Slocum ST, Che T, Gavin AC, McCorvy JD, Roth BL, Strachan RT. Olsen RHJ, et al. Among authors: english jg. Nat Chem Biol. 2020 Aug;16(8):841-849. doi: 10.1038/s41589-020-0535-8. Epub 2020 May 4. Nat Chem Biol. 2020. PMID: 32367019 Free PMC article.
Structure, function and pharmacology of human itch GPCRs.
Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL. Cao C, et al. Among authors: english jg. Nature. 2021 Dec;600(7887):170-175. doi: 10.1038/s41586-021-04126-6. Epub 2021 Nov 17. Nature. 2021. PMID: 34789874 Free PMC article.
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.
Nagai Y, Miyakawa N, Takuwa H, Hori Y, Oyama K, Ji B, Takahashi M, Huang XP, Slocum ST, DiBerto JF, Xiong Y, Urushihata T, Hirabayashi T, Fujimoto A, Mimura K, English JG, Liu J, Inoue KI, Kumata K, Seki C, Ono M, Shimojo M, Zhang MR, Tomita Y, Nakahara J, Suhara T, Takada M, Higuchi M, Jin J, Roth BL, Minamimoto T. Nagai Y, et al. Among authors: english jg. Nat Neurosci. 2020 Sep;23(9):1157-1167. doi: 10.1038/s41593-020-0661-3. Epub 2020 Jul 6. Nat Neurosci. 2020. PMID: 32632286
Ion-ing out the genetic variants of Kir2.1.
Fallon BS, English JG. Fallon BS, et al. Among authors: english jg. Elife. 2022 Jul 11;11:e80718. doi: 10.7554/eLife.80718. Elife. 2022. PMID: 35816168 Free PMC article.
Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters.
Zahm AM, Owens WS, Himes SR, Rondem KE, Fallon BS, Gormick AN, Bloom JS, Kosuri S, Chan H, English JG. Zahm AM, et al. Among authors: english jg. bioRxiv [Preprint]. 2023 May 11:2023.05.11.539703. doi: 10.1101/2023.05.11.539703. bioRxiv. 2023. PMID: 37214829 Free PMC article. Preprint.
VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.
English JG, Olsen RHJ, Lansu K, Patel M, White K, Cockrell AS, Singh D, Strachan RT, Wacker D, Roth BL. English JG, et al. Cell. 2019 Jul 25;178(3):748-761.e17. doi: 10.1016/j.cell.2019.05.051. Epub 2019 Jul 4. Cell. 2019. PMID: 31280962 Free PMC article.
13 results