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Mechanisms of HCV resistance to broadly neutralizing antibodies.
Frumento N, Flyak AI, Bailey JR. Frumento N, et al. Among authors: flyak ai. Curr Opin Virol. 2021 Oct;50:23-29. doi: 10.1016/j.coviro.2021.07.003. Epub 2021 Jul 28. Curr Opin Virol. 2021. PMID: 34329953 Free PMC article. Review.
Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Bozhanova NG, Flyak AI, Brown BP, Ruiz SE, Salas J, Rho S, Bombardi RG, Myers L, Soto C, Bailey JR, Crowe JE Jr, Bjorkman PJ, Meiler J. Bozhanova NG, et al. Among authors: flyak ai. Nat Commun. 2022 Jun 8;13(1):3178. doi: 10.1038/s41467-022-30865-9. Nat Commun. 2022. PMID: 35676279 Free PMC article. Review.
Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Weber T, Potthoff J, Bizu S, Labuhn M, Dold L, Schoofs T, Horning M, Ercanoglu MS, Kreer C, Gieselmann L, Vanshylla K, Langhans B, Janicki H, Ströh LJ, Knops E, Nierhoff D, Spengler U, Kaiser R, Bjorkman PJ, Krey T, Bankwitz D, Pfeifer N, Pietschmann T, Flyak AI, Klein F. Weber T, et al. Among authors: flyak ai. Immunity. 2022 Feb 8;55(2):341-354.e7. doi: 10.1016/j.immuni.2021.12.003. Epub 2022 Jan 5. Immunity. 2022. PMID: 34990590 Free PMC article.
Mechanism of human antibody-mediated neutralization of Marburg virus.
Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE Jr. Flyak AI, et al. Cell. 2015 Feb 26;160(5):893-903. doi: 10.1016/j.cell.2015.01.031. Cell. 2015. PMID: 25723164 Free PMC article.
Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection.
Kinchen VJ, Zahid MN, Flyak AI, Soliman MG, Learn GH, Wang S, Davidson E, Doranz BJ, Ray SC, Cox AL, Crowe JE Jr, Bjorkman PJ, Shaw GM, Bailey JR. Kinchen VJ, et al. Among authors: flyak ai. Cell Host Microbe. 2018 Nov 14;24(5):717-730.e5. doi: 10.1016/j.chom.2018.10.012. Cell Host Microbe. 2018. PMID: 30439341 Free PMC article.
37 results