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Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH.
Fernández-Ginés R, Encinar JA, Escoll M, Carnicero-Senabre D, Jiménez-Villegas J, García-Yagüe ÁJ, González-Rodríguez Á, Garcia-Martinez I, Valverde ÁM, Rojo AI, Cuadrado A. Fernández-Ginés R, et al. Among authors: garcia yague aj. Redox Biol. 2024 Feb;69:103027. doi: 10.1016/j.redox.2024.103027. Epub 2024 Jan 3. Redox Biol. 2024. PMID: 38184999 Free PMC article.
Can Activation of NRF2 Be a Strategy against COVID-19?
Cuadrado A, Pajares M, Benito C, Jiménez-Villegas J, Escoll M, Fernández-Ginés R, Garcia Yagüe AJ, Lastra D, Manda G, Rojo AI, Dinkova-Kostova AT. Cuadrado A, et al. Among authors: garcia yague aj. Trends Pharmacol Sci. 2020 Sep;41(9):598-610. doi: 10.1016/j.tips.2020.07.003. Epub 2020 Jul 14. Trends Pharmacol Sci. 2020. PMID: 32711925 Free PMC article. Review.
Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.
Pajares M, Jiménez-Moreno N, García-Yagüe ÁJ, Escoll M, de Ceballos ML, Van Leuven F, Rábano A, Yamamoto M, Rojo AI, Cuadrado A. Pajares M, et al. Among authors: garcia yague aj. Autophagy. 2016 Oct 2;12(10):1902-1916. doi: 10.1080/15548627.2016.1208889. Epub 2016 Jul 18. Autophagy. 2016. PMID: 27427974 Free PMC article.
Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.
Herrera-Arozamena C, Estrada-Valencia M, Pérez C, Lagartera L, Morales-García JA, Pérez-Castillo A, Franco-Gonzalez JF, Michalska P, Duarte P, León R, López MG, Mills A, Gago F, García-Yagüe ÁJ, Fernández-Ginés R, Cuadrado A, Rodríguez-Franco MI. Herrera-Arozamena C, et al. Among authors: garcia yague aj. Eur J Med Chem. 2020 Mar 15;190:112090. doi: 10.1016/j.ejmech.2020.112090. Epub 2020 Jan 25. Eur J Med Chem. 2020. PMID: 32018096 Free article.
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