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Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression.
Chandrashekar DS, Chakravarthi BVSK, Robinson AD, Anderson JC, Agarwal S, Balasubramanya SAH, Eich ML, Bajpai AK, Davuluri S, Guru MS, Guru AS, Naik G, Della Manna DL, Acharya KK, Carskadon S, Manne U, Crossman DK, Ferguson JE, Grizzle WE, Palanisamy N, Willey CD, Crowley MR, Netto GJ, Yang ES, Varambally S, Sonpavde G. Chandrashekar DS, et al. Among authors: guru as. Oncogene. 2020 May;39(20):4077-4091. doi: 10.1038/s41388-020-1275-7. Epub 2020 Mar 30. Oncogene. 2020. PMID: 32231273
Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets.
Ghatalia P, Yang ES, Lasseigne BN, Ramaker RC, Cooper SJ, Chen D, Sudarshan S, Wei S, Guru AS, Zhao A, Cooper T, Della Manna DL, Naik G, Myers RM, Sonpavde G. Ghatalia P, et al. Among authors: guru as. PLoS One. 2016 Aug 30;11(8):e0160924. doi: 10.1371/journal.pone.0160924. eCollection 2016. PLoS One. 2016. PMID: 27574806 Free PMC article.