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Page 1
Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.
Krücken J, Holden-Dye L, Keiser J, Prichard RK, Townson S, Makepeace BL, Hübner MP, Hahnel SR, Scandale I, Harder A, Kulke D. Krücken J, et al. Among authors: hahnel sr. PLoS Pathog. 2021 Jul 22;17(7):e1009682. doi: 10.1371/journal.ppat.1009682. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34293063 Free PMC article. Review.
Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside.
Hübner MP, Townson S, Gokool S, Tagboto S, Maclean MJ, Verocai GG, Wolstenholme AJ, Frohberger SJ, Hoerauf A, Specht S, Scandale I, Harder A, Glenschek-Sieberth M, Hahnel SR, Kulke D. Hübner MP, et al. Among authors: hahnel sr. Int J Parasitol Drugs Drug Resist. 2021 Dec;17:27-35. doi: 10.1016/j.ijpddr.2021.07.005. Epub 2021 Jul 28. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34339934 Free PMC article.
Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram.
Beutler M, Harnischfeger J, Weber MHW, Hahnel SR, Quack T, Blohm A, Ueberall ME, Timm T, Lochnit G, Rennar GA, Gallinger TL, Houhou H, Rahlfs S, Falcone FH, Becker K, Schlitzer M, Haeberlein S, Czermak P, Salzig D, Grevelding CG. Beutler M, et al. Among authors: hahnel sr. Eur J Med Chem. 2023 May 5;251:115179. doi: 10.1016/j.ejmech.2023.115179. Epub 2023 Feb 10. Eur J Med Chem. 2023. PMID: 36948075 Free article.
Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.
Bah GS, Schneckener S, Hahnel SR, Bayang NH, Fieseler H, Schmuck GM, Krebber R, Sarr A, Terjung C, Ngangyung HF, Ekale DD, Mfopit YM, Rufener L, Graham-Brown J, Tanya VN, Glenschek-Sieberth M, Kulke D, Makepeace BL. Bah GS, et al. Among authors: hahnel sr. PLoS Pathog. 2021 Jun 2;17(6):e1009601. doi: 10.1371/journal.ppat.1009601. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34077488 Free PMC article.
12 results