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Page 1
Transient activation of the UPRER is an essential step in the acquisition of pluripotency during reprogramming.
Sci Adv. 2019 Apr 10;5(4):eaaw0025. doi: 10.1126/sciadv.aaw0025. eCollection 2019 Apr.
Sci Adv. 2019.
PMID: 30989118
Free PMC article.
mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging.
Van Skike CE, Lin AL, Roberts Burbank R, Halloran JJ, Hernandez SF, Cuvillier J, Soto VY, Hussong SA, Jahrling JB, Javors MA, Hart MJ, Fischer KE, Austad SN, Galvan V.
Van Skike CE, et al. Among authors: halloran jj.
Aging Cell. 2020 Jan;19(1):e13057. doi: 10.1111/acel.13057. Epub 2019 Nov 6.
Aging Cell. 2020.
PMID: 31693798
Free PMC article.
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Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice.
Lin AL, Pulliam DA, Deepa SS, Halloran JJ, Hussong SA, Burbank RR, Bresnen A, Liu Y, Podlutskaya N, Soundararajan A, Muir E, Duong TQ, Bokov AF, Viscomi C, Zeviani M, Richardson AG, Van Remmen H, Fox PT, Galvan V.
Lin AL, et al. Among authors: halloran jj.
J Cereb Blood Flow Metab. 2013 Oct;33(10):1605-11. doi: 10.1038/jcbfm.2013.116. Epub 2013 Jul 10.
J Cereb Blood Flow Metab. 2013.
PMID: 23838831
Free PMC article.
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Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease.
Pierce A, Podlutskaya N, Halloran JJ, Hussong SA, Lin PY, Burbank R, Hart MJ, Galvan V.
Pierce A, et al. Among authors: halloran jj.
J Neurochem. 2013 Mar;124(6):880-93. doi: 10.1111/jnc.12080. Epub 2012 Dec 26.
J Neurochem. 2013.
PMID: 23121022
Free PMC article.
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Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.
Lin AL, Zheng W, Halloran JJ, Burbank RR, Hussong SA, Hart MJ, Javors M, Shih YY, Muir E, Solano Fonseca R, Strong R, Richardson AG, Lechleiter JD, Fox PT, Galvan V.
Lin AL, et al. Among authors: halloran jj.
J Cereb Blood Flow Metab. 2013 Sep;33(9):1412-21. doi: 10.1038/jcbfm.2013.82. Epub 2013 Jun 26.
J Cereb Blood Flow Metab. 2013.
PMID: 23801246
Free PMC article.
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