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Bi-allelic variants in DOHH, catalyzing the last step of hypusine biosynthesis, are associated with a neurodevelopmental disorder.
Am J Hum Genet. 2022 Aug 4;109(8):1549-1558. doi: 10.1016/j.ajhg.2022.06.010. Epub 2022 Jul 19.
Am J Hum Genet. 2022.
PMID: 35858628
Free PMC article.
Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.
Kar RK, Hanner AS, Starost MF, Springer D, Mastracci TL, Mirmira RG, Park MH.
Kar RK, et al. Among authors: hanner as.
J Biol Chem. 2021 Nov;297(5):101333. doi: 10.1016/j.jbc.2021.101333. Epub 2021 Oct 22.
J Biol Chem. 2021.
PMID: 34688659
Free PMC article.
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Elevation of cellular Mg2+ levels by the Mg2+ transporter, Alr1, supports growth of polyamine-deficient Saccharomyces cerevisiae cells.
Hanner AS, Dunworth M, Casero RA Jr, MacDiarmid CW, Park MH.
Hanner AS, et al.
J Biol Chem. 2019 Nov 8;294(45):17131-17142. doi: 10.1074/jbc.RA119.009705. Epub 2019 Sep 22.
J Biol Chem. 2019.
PMID: 31548311
Free PMC article.
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The Yeast Heterochromatin Protein Sir3 Experienced Functional Changes in the AAA+ Domain After Gene Duplication and Subfunctionalization.
Hanner AS, Rusche LN.
Hanner AS, et al.
Genetics. 2017 Oct;207(2):517-528. doi: 10.1534/genetics.117.300180. Epub 2017 Aug 21.
Genetics. 2017.
PMID: 28827288
Free PMC article.
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