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Gi-coupled receptor activation potentiates Piezo2 currents via Gβγ.
Del Rosario JS, Yudin Y, Su S, Hartle CM, Mirshahi T, Rohacs T. Del Rosario JS, et al. Among authors: hartle cm. EMBO Rep. 2020 May 6;21(5):e49124. doi: 10.15252/embr.201949124. Epub 2020 Mar 29. EMBO Rep. 2020. PMID: 32227462 Free PMC article.
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.
Gusarova V, O'Dushlaine C, Teslovich TM, Benotti PN, Mirshahi T, Gottesman O, Van Hout CV, Murray MF, Mahajan A, Nielsen JB, Fritsche L, Wulff AB, Gudbjartsson DF, Sjögren M, Emdin CA, Scott RA, Lee WJ, Small A, Kwee LC, Dwivedi OP, Prasad RB, Bruse S, Lopez AE, Penn J, Marcketta A, Leader JB, Still CD, Kirchner HL, Mirshahi UL, Wardeh AH, Hartle CM, Habegger L, Fetterolf SN, Tusie-Luna T, Morris AP, Holm H, Steinthorsdottir V, Sulem P, Thorsteinsdottir U, Rotter JI, Chuang LM, Damrauer S, Birtwell D, Brummett CM, Khera AV, Natarajan P, Orho-Melander M, Flannick J, Lotta LA, Willer CJ, Holmen OL, Ritchie MD, Ledbetter DH, Murphy AJ, Borecki IB, Reid JG, Overton JD, Hansson O, Groop L, Shah SH, Kraus WE, Rader DJ, Chen YI, Hveem K, Wareham NJ, Kathiresan S, Melander O, Stefansson K, Nordestgaard BG, Tybjærg-Hansen A, Abecasis GR, Altshuler D, Florez JC, Boehnke M, McCarthy MI, Yancopoulos GD, Carey DJ, Shuldiner AR, Baras A, Dewey FE, Gromada J. Gusarova V, et al. Among authors: hartle cm. Nat Commun. 2018 Jun 13;9(1):2252. doi: 10.1038/s41467-018-04611-z. Nat Commun. 2018. PMID: 29899519 Free PMC article.
CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions.
Krumbholz M, Theil D, Steinmeyer F, Cepok S, Hemmer B, Hofbauer M, Farina C, Derfuss T, Junker A, Arzberger T, Sinicina I, Hartle C, Newcombe J, Hohlfeld R, Meinl E. Krumbholz M, et al. Among authors: hartle c. J Neuroimmunol. 2007 Oct;190(1-2):72-9. doi: 10.1016/j.jneuroim.2007.07.024. Epub 2007 Sep 6. J Neuroimmunol. 2007. PMID: 17825430
11 results