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Page 1
Accelerated waning of the humoral response to COVID-19 vaccines in obesity.
Nat Med. 2023 May;29(5):1146-1154. doi: 10.1038/s41591-023-02343-2. Epub 2023 May 11.
Nat Med. 2023.
PMID: 37169862
Free PMC article.
The receptor PTPRU is a redox sensitive pseudophosphatase.
Hay IM, Fearnley GW, Rios P, Köhn M, Sharpe HJ, Deane JE.
Hay IM, et al.
Nat Commun. 2020 Jun 26;11(1):3219. doi: 10.1038/s41467-020-17076-w.
Nat Commun. 2020.
PMID: 32591542
Free PMC article.
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Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain.
Hay IM, Mulholland KE, Lai T, Graham SC, Sharpe HJ, Deane JE.
Hay IM, et al.
Elife. 2022 Oct 20;11:e79855. doi: 10.7554/eLife.79855.
Elife. 2022.
PMID: 36264065
Free PMC article.
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Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
Hay IM, Shamin M, Caroe ER, Mohammed ASA, Svergun DI, Jeffries CM, Graham SC, Sharpe HJ, Deane JE.
Hay IM, et al.
J Biol Chem. 2023 Jan;299(1):102750. doi: 10.1016/j.jbc.2022.102750. Epub 2022 Nov 25.
J Biol Chem. 2023.
PMID: 36436563
Free PMC article.
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Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination.
Foster WS, Lee JL, Thakur N, Newman J, Spencer AJ, Davies S, Woods D, Godfrey L, Hay IM, Innocentin S, Yam-Puc JC, Horner EC, Sharpe HJ, Thaventhiran JE, Bailey D, Lambe T, Linterman MA.
Foster WS, et al. Among authors: hay im.
Cell Rep Med. 2022 Dec 20;3(12):100845. doi: 10.1016/j.xcrm.2022.100845. Epub 2022 Nov 15.
Cell Rep Med. 2022.
PMID: 36455555
Free PMC article.
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The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion.
Fearnley GW, Young KA, Edgar JR, Antrobus R, Hay IM, Liang WC, Martinez-Martin N, Lin W, Deane JE, Sharpe HJ.
Fearnley GW, et al. Among authors: hay im.
Elife. 2019 Mar 29;8:e44597. doi: 10.7554/eLife.44597.
Elife. 2019.
PMID: 30924770
Free PMC article.
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