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Temporal-iCLIP captures co-transcriptional RNA-protein interactions.
Cordiner RA, Dou Y, Thomsen R, Bugai A, Granneman S, Heick Jensen T. Cordiner RA, et al. Among authors: heick jensen t. Nat Commun. 2023 Feb 8;14(1):696. doi: 10.1038/s41467-023-36345-y. Nat Commun. 2023. PMID: 36755023 Free PMC article.
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G4C2)exp in c9ALS/FTD via the nuclear RNA exosome.
Bush JA, Meyer SM, Fuerst R, Tong Y, Li Y, Benhamou RI, Aikawa H, Zanon PRA, Gibaut QMR, Angelbello AJ, Gendron TF, Zhang YJ, Petrucelli L, Heick Jensen T, Childs-Disney JL, Disney MD. Bush JA, et al. Among authors: heick jensen t. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2210532119. doi: 10.1073/pnas.2210532119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36409902 Free PMC article.
Mapping domains of ARS2 critical for its RNA decay capacity.
Melko M, Winczura K, Rouvière JO, Oborská-Oplová M, Andersen PK, Heick Jensen T. Melko M, et al. Among authors: heick jensen t. Nucleic Acids Res. 2020 Jul 9;48(12):6943-6953. doi: 10.1093/nar/gkaa445. Nucleic Acids Res. 2020. PMID: 32463452 Free PMC article.