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Page 1
Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides.
Edgar RJ, van Hensbergen VP, Ruda A, Turner AG, Deng P, Le Breton Y, El-Sayed NM, Belew AT, McIver KS, McEwan AG, Morris AJ, Lambeau G, Walker MJ, Rush JS, Korotkov KV, Widmalm G, van Sorge NM, Korotkova N. Edgar RJ, et al. Among authors: van hensbergen vp. Nat Chem Biol. 2019 May;15(5):463-471. doi: 10.1038/s41589-019-0251-4. Epub 2019 Apr 1. Nat Chem Biol. 2019. PMID: 30936502 Free PMC article.
Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes.
Heesterbeek DAC, Muts RM, van Hensbergen VP, de Saint Aulaire P, Wennekes T, Bardoel BW, van Sorge NM, Rooijakkers SHM. Heesterbeek DAC, et al. Among authors: van hensbergen vp. PLoS Pathog. 2021 Jan 22;17(1):e1009227. doi: 10.1371/journal.ppat.1009227. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33481964 Free PMC article.
Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant Staphylococcus aureus to Human Group IIA-Secreted Phospholipase A2 and Daptomycin.
Kuijk MM, Wu Y, van Hensbergen VP, Shanlitourk G, Payré C, Lambeau G, Man-Bovenkerk S, Herrmann J, Müller R, van Strijp JAG, Pannekoek Y, Touqui L, van Sorge NM. Kuijk MM, et al. Among authors: van hensbergen vp. J Innate Immun. 2023;15(1):333-350. doi: 10.1159/000527549. Epub 2022 Dec 6. J Innate Immun. 2023. PMID: 36473432 Free PMC article.
Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects.
van Hensbergen VP, Movert E, de Maat V, Lüchtenborg C, Le Breton Y, Lambeau G, Payré C, Henningham A, Nizet V, van Strijp JAG, Brügger B, Carlsson F, McIver KS, van Sorge NM. van Hensbergen VP, et al. PLoS Pathog. 2018 Oct 15;14(10):e1007348. doi: 10.1371/journal.ppat.1007348. eCollection 2018 Oct. PLoS Pathog. 2018. PMID: 30321240 Free PMC article.