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Page 1
Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport.
Florido J, Martinez-Ruiz L, Rodriguez-Santana C, López-Rodríguez A, Hidalgo-Gutiérrez A, Cottet-Rousselle C, Lamarche F, Schlattner U, Guerra-Librero A, Aranda-Martínez P, Acuña-Castroviejo D, López LC, Escames G. Florido J, et al. Among authors: hidalgo gutierrez a. J Pineal Res. 2022 Oct;73(3):e12824. doi: 10.1111/jpi.12824. Epub 2022 Aug 28. J Pineal Res. 2022. PMID: 35986493 Free PMC article.
Metabolic Targets of Coenzyme Q10 in Mitochondria.
Hidalgo-Gutiérrez A, González-García P, Díaz-Casado ME, Barriocanal-Casado E, López-Herrador S, Quinzii CM, López LC. Hidalgo-Gutiérrez A, et al. Antioxidants (Basel). 2021 Mar 26;10(4):520. doi: 10.3390/antiox10040520. Antioxidants (Basel). 2021. PMID: 33810539 Free PMC article. Review.
The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency.
González-García P, Díaz-Casado ME, Hidalgo-Gutiérrez A, Jiménez-Sánchez L, Bakkali M, Barriocanal-Casado E, Escames G, Chiozzi RZ, Völlmy F, Zaal EA, Berkers CR, Heck AJR, López LC. González-García P, et al. Among authors: hidalgo gutierrez a. Redox Biol. 2022 Sep;55:102403. doi: 10.1016/j.redox.2022.102403. Epub 2022 Jul 15. Redox Biol. 2022. PMID: 35863266 Free PMC article.
Animal Models of Coenzyme Q Deficiency: Mechanistic and Translational Learnings.
González-García P, Barriocanal-Casado E, Díaz-Casado ME, López-Herrador S, Hidalgo-Gutiérrez A, López LC. González-García P, et al. Among authors: hidalgo gutierrez a. Antioxidants (Basel). 2021 Oct 26;10(11):1687. doi: 10.3390/antiox10111687. Antioxidants (Basel). 2021. PMID: 34829558 Free PMC article. Review.
β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9R239X mice.
Hidalgo-Gutiérrez A, Barriocanal-Casado E, Bakkali M, Díaz-Casado ME, Sánchez-Maldonado L, Romero M, Sayed RK, Prehn C, Escames G, Duarte J, Acuña-Castroviejo D, López LC. Hidalgo-Gutiérrez A, et al. EMBO Mol Med. 2019 Jan;11(1):e9466. doi: 10.15252/emmm.201809466. EMBO Mol Med. 2019. PMID: 30482867 Free PMC article.
CoQ10 supplementation rescues nephrotic syndrome through normalization of H2S oxidation pathway.
Kleiner G, Barca E, Ziosi M, Emmanuele V, Xu Y, Hidalgo-Gutierrez A, Qiao C, Tadesse S, Area-Gomez E, Lopez LC, Quinzii CM. Kleiner G, et al. Among authors: hidalgo gutierrez a. Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3708-3722. doi: 10.1016/j.bbadis.2018.09.002. Epub 2018 Sep 6. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30251690 Free PMC article.
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