Houliston S[au] - Search Results

Year	Number of Results
2006	1
2007	1
2010	1
2011	1
2012	1
2013	3
2014	4
2015	1
2016	1
2017	3
2018	2
2019	3
2020	1
2021	1
2022	5
2023	1
2024	1

1

De novo design of immunoglobulin-like domains.

Chidyausiku TM, Mendes SR, Klima JC, Nadal M, Eckhard U, Roel-Touris J, Houliston S, Guevara T, Haddox HK, Moyer A, Arrowsmith CH, Gomis-Rüth FX, Baker D, Marcos E. Chidyausiku TM, et al. Among authors: houliston s. Nat Commun. 2022 Oct 3;13(1):5661. doi: 10.1038/s41467-022-33004-6. Nat Commun. 2022. PMID: 36192397 Free PMC article.

2

The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.

Wei Y, Redel C, Ahlner A, Lemak A, Johansson-Åkhe I, Houliston S, Kenney TMG, Tamachi A, Morad V, Duan S, Andrews DW, Wallner B, Sunnerhagen M, Arrowsmith CH, Penn LZ. Wei Y, et al. Among authors: houliston s. Nucleic Acids Res. 2022 Apr 8;50(6):3505-3522. doi: 10.1093/nar/gkac138. Nucleic Acids Res. 2022. PMID: 35244724 Free PMC article.

3

Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease.

Payliss BJ, Tse YWE, Reichheld SE, Lemak A, Yun HY, Houliston S, Patel A, Arrowsmith CH, Sharpe S, Wyatt HDM. Payliss BJ, et al. Among authors: houliston s. Cell Rep. 2022 Oct 25;41(4):111537. doi: 10.1016/j.celrep.2022.111537. Cell Rep. 2022. PMID: 36288699 Free article.

4

Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.

Tauber M, Kreuz S, Lemak A, Mandal P, Yerkesh Z, Veluchamy A, Al-Gashgari B, Aljahani A, Cortés-Medina LV, Azhibek D, Fan L, Ong MS, Duan S, Houliston S, Arrowsmith CH, Fischle W. Tauber M, et al. Among authors: houliston s. Nucleic Acids Res. 2020 Aug 20;48(14):7728-7747. doi: 10.1093/nar/gkaa520. Nucleic Acids Res. 2020. PMID: 32609811 Free PMC article.

5

Identification and characterization of the first fragment hits for SETDB1 Tudor domain.

Mader P, Mendoza-Sanchez R, Iqbal A, Dong A, Dobrovetsky E, Corless VB, Liew SK, Houliston SR, De Freitas RF, Smil D, Sena CCD, Kennedy S, Diaz DB, Wu H, Dombrovski L, Allali-Hassani A, Min J, Schapira M, Vedadi M, Brown PJ, Santhakumar V, Yudin AK, Arrowsmith CH. Mader P, et al. Among authors: houliston sr. Bioorg Med Chem. 2019 Sep 1;27(17):3866-3878. doi: 10.1016/j.bmc.2019.07.020. Epub 2019 Jul 12. Bioorg Med Chem. 2019. PMID: 31327677

6

Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain.

Mann MK, Franzoni I, de Freitas RF, Tempel W, Houliston S, Smith L, Vedadi M, Arrowsmith CH, Harding RJ, Schapira M. Mann MK, et al. Among authors: houliston s. J Med Chem. 2019 Nov 27;62(22):10144-10155. doi: 10.1021/acs.jmedchem.9b00988. Epub 2019 Nov 12. J Med Chem. 2019. PMID: 31663737

7

The RavA-ViaA chaperone complex modulates bacterial persistence through its association with the fumarate reductase enzyme.

Bhandari V, Reichheld SE, Houliston S, Lemak A, Arrowsmith CH, Sharpe S, Houry WA. Bhandari V, et al. Among authors: houliston s. J Biol Chem. 2023 Oct;299(10):105199. doi: 10.1016/j.jbc.2023.105199. Epub 2023 Sep 3. J Biol Chem. 2023. PMID: 37660904 Free PMC article.

8

Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.

Kim TE, Tsuboyama K, Houliston S, Martell CM, Phoumyvong CM, Lemak A, Haddox HK, Arrowsmith CH, Rocklin GJ. Kim TE, et al. Among authors: houliston s. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2122676119. doi: 10.1073/pnas.2122676119. Epub 2022 Oct 3. Proc Natl Acad Sci U S A. 2022. PMID: 36191185 Free PMC article.

9

Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence.

Peng X, Baxa M, Faruk N, Sachleben JR, Pintscher S, Gagnon IA, Houliston S, Arrowsmith CH, Freed KF, Rocklin GJ, Sosnick TR. Peng X, et al. Among authors: houliston s. J Chem Theory Comput. 2022 Jan 11;18(1):550-561. doi: 10.1021/acs.jctc.1c00960. Epub 2021 Dec 22. J Chem Theory Comput. 2022. PMID: 34936354 Free PMC article.

10

The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA.

Yin JZ, Keszei AFA, Houliston S, Filandr F, Beenstock J, Daou S, Kitaygorodsky J, Schriemer DC, Mazhab-Jafari MT, Gingras AC, Sicheri F. Yin JZ, et al. Among authors: houliston s. Structure. 2024 Mar 22:S0969-2126(24)00081-9. doi: 10.1016/j.str.2024.02.021. Online ahead of print. Structure. 2024. PMID: 38531363

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