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Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.
Soeda K, Sasako T, Enooku K, Kubota N, Kobayashi N, Ikushima YM, Awazawa M, Bouchi R, Toda G, Yamada T, Nakatsuka T, Tateishi R, Kakiuchi M, Yamamoto S, Tatsuno K, Atarashi K, Suda W, Honda K, Aburatani H, Yamauchi T, Fujishiro M, Noda T, Koike K, Kadowaki T, Ueki K. Soeda K, et al. Among authors: ikushima ym. Nat Commun. 2023 Oct 18;14(1):6584. doi: 10.1038/s41467-023-42334-y. Nat Commun. 2023. PMID: 37852976 Free PMC article.
The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent.
Suchacki KJ, Thomas BJ, Ikushima YM, Chen KC, Fyfe C, Tavares AAS, Sulston RJ, Lovdel A, Woodward HJ, Han X, Mattiucci D, Brain EJ, Alcaide-Corral CJ, Kobayashi H, Gray GA, Whitfield PD, Stimson RH, Morton NM, Johnstone AM, Cawthorn WP. Suchacki KJ, et al. Among authors: ikushima ym. Elife. 2023 Apr 25;12:e88080. doi: 10.7554/eLife.88080. Elife. 2023. PMID: 37096321 Free PMC article.
An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance.
Matsushita M, Awazawa M, Kobayashi N, Ikushima YM, Soeda K, Tamura-Nakano M, Muratani M, Kobayashi K, Blüher M, Brüning JC, Ueki K. Matsushita M, et al. Among authors: ikushima ym. Cell Chem Biol. 2022 Apr 21;29(4):680-689.e6. doi: 10.1016/j.chembiol.2021.12.008. Epub 2022 Jan 4. Cell Chem Biol. 2022. PMID: 34986326 Free article.