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Page 1
Redox driven B12-ligand switch drives CarH photoresponse.
Poddar H, Rios-Santacruz R, Heyes DJ, Shanmugam M, Brookfield A, Johannissen LO, Levy CW, Jeffreys LN, Zhang S, Sakuma M, Colletier JP, Hay S, Schirò G, Weik M, Scrutton NS, Leys D. Poddar H, et al. Among authors: jeffreys ln. Nat Commun. 2023 Aug 21;14(1):5082. doi: 10.1038/s41467-023-40817-6. Nat Commun. 2023. PMID: 37604813 Free PMC article.
Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2.
Jeffreys LN, Pennington SH, Duggan J, Caygill CH, Lopeman RC, Breen AF, Jinks JB, Ardrey A, Donnellan S, Patterson EI, Hughes GL, Hong DW, O'Neill PM, Aljayyoussi G, Owen A, Ward SA, Biagini GA. Jeffreys LN, et al. Int J Antimicrob Agents. 2022 Mar;59(3):106542. doi: 10.1016/j.ijantimicag.2022.106542. Epub 2022 Jan 31. Int J Antimicrob Agents. 2022. PMID: 35093538 Free PMC article.
Photocobilins integrate B12 and bilin photochemistry for enzyme control.
Zhang S, Jeffreys LN, Poddar H, Yu Y, Liu C, Patel K, Johannissen LO, Zhu L, Cliff MJ, Yan C, Schirò G, Weik M, Sakuma M, Levy CW, Leys D, Heyes DJ, Scrutton NS. Zhang S, et al. Among authors: jeffreys ln. Nat Commun. 2024 Mar 28;15(1):2740. doi: 10.1038/s41467-024-46995-1. Nat Commun. 2024. PMID: 38548733 Free PMC article.
Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis.
Jeffreys LN, Ardrey A, Hafiz TA, Dyer LA, Warman AJ, Mosallam N, Nixon GL, Fisher NE, Hong WD, Leung SC, Aljayyoussi G, Bibby J, Almeida DV, Converse PJ, Fotouhi N, Berry NG, Nuermberger EL, Upton AM, O'Neill PM, Ward SA, Biagini GA. Jeffreys LN, et al. ACS Infect Dis. 2023 Feb 10;9(2):221-238. doi: 10.1021/acsinfecdis.2c00283. Epub 2023 Jan 6. ACS Infect Dis. 2023. PMID: 36606559 Free PMC article.
Pathogen webs in collapsing honey bee colonies.
Cornman RS, Tarpy DR, Chen Y, Jeffreys L, Lopez D, Pettis JS, vanEngelsdorp D, Evans JD. Cornman RS, et al. Among authors: jeffreys l. PLoS One. 2012;7(8):e43562. doi: 10.1371/journal.pone.0043562. Epub 2012 Aug 21. PLoS One. 2012. PMID: 22927991 Free PMC article.
Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors.
González-Paz L, Alvarado MJ, Hurtado-León ML, Lossada C, Vera-Villalobos J, Loroño M, Paz JL, Jeffreys LN, Torres FJ, Alvarado YJ. González-Paz L, et al. Among authors: jeffreys ln. Comput Biol Med. 2022 Mar;142:105245. doi: 10.1016/j.compbiomed.2022.105245. Epub 2022 Jan 20. Comput Biol Med. 2022. PMID: 35077937 Free PMC article.
Comparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach.
González-Paz L, Hurtado-León ML, Lossada C, Fernández-Materán FV, Vera-Villalobos J, Loroño M, Paz JL, Jeffreys L, Alvarado YJ. González-Paz L, et al. Among authors: jeffreys l. Biophys Chem. 2021 Nov;278:106677. doi: 10.1016/j.bpc.2021.106677. Epub 2021 Aug 19. Biophys Chem. 2021. PMID: 34428682 Free PMC article.
19 results