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Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain.
Tassou A, Thouaye M, Gilabert D, Jouvenel A, Leyris JP, Sonrier C, Diouloufet L, Mechaly I, Mallié S, Bertin J, Chentouf M, Neiveyans M, Pugnière M, Martineau P, Robert B, Capdevila X, Valmier J, Rivat C. Tassou A, et al. Among authors: jouvenel a. Prog Neurobiol. 2023 Mar;222:102405. doi: 10.1016/j.pneurobio.2023.102405. Epub 2023 Jan 13. Prog Neurobiol. 2023. PMID: 36646299 Free article.
AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A.
Gautier B, Hajjar H, Soares S, Berthelot J, Deck M, Abbou S, Campbell G, Ceprian M, Gonzalez S, Fovet CM, Schütza V, Jouvenel A, Rivat C, Zerah M, François V, Le Guiner C, Aubourg P, Fledrich R, Tricaud N. Gautier B, et al. Among authors: jouvenel a. Nat Commun. 2021 Apr 21;12(1):2356. doi: 10.1038/s41467-021-22593-3. Nat Commun. 2021. PMID: 33883545 Free PMC article.
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice.
Rivat C, Sar C, Mechaly I, Leyris JP, Diouloufet L, Sonrier C, Philipson Y, Lucas O, Mallié S, Jouvenel A, Tassou A, Haton H, Venteo S, Pin JP, Trinquet E, Charrier-Savournin F, Mezghrani A, Joly W, Mion J, Schmitt M, Pattyn A, Marmigère F, Sokoloff P, Carroll P, Rognan D, Valmier J. Rivat C, et al. Among authors: jouvenel a. Nat Commun. 2018 Mar 12;9(1):1042. doi: 10.1038/s41467-018-03496-2. Nat Commun. 2018. PMID: 29531216 Free PMC article.