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Barriers to accessing public cancer genomic data.
Learned K, Durbin A, Currie R, Kephart ET, Beale HC, Sanders LM, Pfeil J, Goldstein TC, Salama SR, Haussler D, Vaske OM, Bjork IM. Learned K, et al. Among authors: kephart et. Sci Data. 2019 Jun 20;6(1):98. doi: 10.1038/s41597-019-0096-4. Sci Data. 2019. PMID: 31222016 Free PMC article.
modMine: flexible access to modENCODE data.
Contrino S, Smith RN, Butano D, Carr A, Hu F, Lyne R, Rutherford K, Kalderimis A, Sullivan J, Carbon S, Kephart ET, Lloyd P, Stinson EO, Washington NL, Perry MD, Ruzanov P, Zha Z, Lewis SE, Stein LD, Micklem G. Contrino S, et al. Among authors: kephart et. Nucleic Acids Res. 2012 Jan;40(Database issue):D1082-8. doi: 10.1093/nar/gkr921. Epub 2011 Nov 12. Nucleic Acids Res. 2012. PMID: 22080565 Free PMC article.
Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors.
Sanders LM, Chandra R, Zebarjadi N, Beale HC, Lyle AG, Rodriguez A, Kephart ET, Pfeil J, Cheney A, Learned K, Currie R, Gitlin L, Vengerov D, Haussler D, Salama SR, Vaske OM. Sanders LM, et al. Among authors: kephart et. Commun Biol. 2022 Dec 13;5(1):1367. doi: 10.1038/s42003-022-04075-4. Commun Biol. 2022. PMID: 36513728 Free PMC article.
Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor.
Sanders LM, Rangaswami A, Bjork I, Lam DL, Beale HC, Kephart ET, Durbin A, Learned K, Currie R, Lyle AG, Pfeil J, Shah AT, Lee AG, Leung SG, Behroozfard IH, Breese MR, Peralez J, Hazard FK, Lacayo N, Spunt SL, Haussler D, Salama SR, Sweet-Cordero EA, Vaske OM. Sanders LM, et al. Among authors: kephart et. Cold Spring Harb Mol Case Stud. 2019 Oct 23;5(5):a004317. doi: 10.1101/mcs.a004317. Print 2019 Oct. Cold Spring Harb Mol Case Stud. 2019. PMID: 31645344 Free PMC article.
Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer.
Vaske OM, Bjork I, Salama SR, Beale H, Tayi Shah A, Sanders L, Pfeil J, Lam DL, Learned K, Durbin A, Kephart ET, Currie R, Newton Y, Swatloski T, McColl D, Vivian J, Zhu J, Lee AG, Leung SG, Spillinger A, Liu HY, Liang WS, Byron SA, Berens ME, Resnick AC, Lacayo N, Spunt SL, Rangaswami A, Huynh V, Torno L, Plant A, Kirov I, Zabokrtsky KB, Rassekh SR, Deyell RJ, Laskin J, Marra MA, Sender LS, Mueller S, Sweet-Cordero EA, Goldstein TC, Haussler D. Vaske OM, et al. Among authors: kephart et. JAMA Netw Open. 2019 Oct 2;2(10):e1913968. doi: 10.1001/jamanetworkopen.2019.13968. JAMA Netw Open. 2019. PMID: 31651965 Free PMC article.
The case for using mapped exonic non-duplicate reads when reporting RNA-sequencing depth: examples from pediatric cancer datasets.
Beale HC, Roger JM, Cattle MA, McKay LT, Thompson DKA, Learned K, Lyle AG, Kephart ET, Currie R, Lam DL, Sanders L, Pfeil J, Vivian J, Bjork I, Salama SR, Haussler D, Vaske OM. Beale HC, et al. Among authors: kephart et. Gigascience. 2021 Mar 13;10(3):giab011. doi: 10.1093/gigascience/giab011. Gigascience. 2021. PMID: 33712853 Free PMC article.
A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma.
Reed MR, Lyle AG, De Loose A, Maddukuri L, Learned K, Beale HC, Kephart ET, Cheney A, van den Bout A, Lee MP, Hundley KN, Smith AM, DesRochers TM, Vibat CRT, Gokden M, Salama S, Wardell CP, Eoff RL, Vaske OM, Rodriguez A. Reed MR, et al. Among authors: kephart et. Cells. 2021 Dec 2;10(12):3400. doi: 10.3390/cells10123400. Cells. 2021. PMID: 34943910 Free PMC article.
Cloud-based uniform ChIP-Seq processing tools for modENCODE and ENCODE.
Trinh QM, Jen FY, Zhou Z, Chu KM, Perry MD, Kephart ET, Contrino S, Ruzanov P, Stein LD. Trinh QM, et al. Among authors: kephart et. BMC Genomics. 2013 Jul 22;14:494. doi: 10.1186/1471-2164-14-494. BMC Genomics. 2013. PMID: 23875683 Free PMC article.