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The β3-integrin endothelial adhesome regulates microtubule-dependent cell migration.
Atkinson SJ, Gontarczyk AM, Alghamdi AA, Ellison TS, Johnson RT, Fowler WJ, Kirkup BM, Silva BC, Harry BE, Schneider JG, Weilbaecher KN, Mogensen MM, Bass MD, Parsons M, Edwards DR, Robinson SD. Atkinson SJ, et al. Among authors: kirkup bm. EMBO Rep. 2018 Jul;19(7):e44578. doi: 10.15252/embr.201744578. Epub 2018 May 24. EMBO Rep. 2018. PMID: 29794156 Free PMC article.
Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth.
McKee AM, Kirkup BM, Madgwick M, Fowler WJ, Price CA, Dreger SA, Ansorge R, Makin KA, Caim S, Le Gall G, Paveley J, Leclaire C, Dalby M, Alcon-Giner C, Andrusaite A, Feng TY, Di Modica M, Triulzi T, Tagliabue E, Milling SWF, Weilbaecher KN, Rutkowski MR, Korcsmáros T, Hall LJ, Robinson SD. McKee AM, et al. Among authors: kirkup bm. iScience. 2021 Aug 20;24(9):103012. doi: 10.1016/j.isci.2021.103012. eCollection 2021 Sep 24. iScience. 2021. PMID: 34522855 Free PMC article.
Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis.
Ellison TS, Atkinson SJ, Steri V, Kirkup BM, Preedy ME, Johnson RT, Ruhrberg C, Edwards DR, Schneider JG, Weilbaecher K, Robinson SD. Ellison TS, et al. Among authors: kirkup bm. Dis Model Mech. 2015 Sep;8(9):1105-19. doi: 10.1242/dmm.019927. Epub 2015 Jul 9. Dis Model Mech. 2015. PMID: 26159543 Free PMC article.