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2013 1
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Page 1
Clinical genome editing to treat sickle cell disease-A brief update.
Zarghamian P, Klermund J, Cathomen T. Zarghamian P, et al. Among authors: klermund j. Front Med (Lausanne). 2023 Jan 9;9:1065377. doi: 10.3389/fmed.2022.1065377. eCollection 2022. Front Med (Lausanne). 2023. PMID: 36698803 Free PMC article. Review.
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1.
Torella L, Klermund J, Bilbao-Arribas M, Tamayo I, Andrieux G, Chmielewski KO, Vales A, Olagüe C, Moreno-Luqui D, Raimondi I, Abad A, Torrens-Baile J, Salido E, Huarte M, Hernaez M, Boerries M, Cathomen T, Zabaleta N, Gonzalez-Aseguinolaza G. Torella L, et al. Among authors: klermund j. EMBO Mol Med. 2024 Jan;16(1):112-131. doi: 10.1038/s44321-023-00008-8. Epub 2024 Jan 5. EMBO Mol Med. 2024. PMID: 38182795 Free PMC article.
Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques.
AlJanahi AA, Lazzarotto CR, Chen S, Shin TH, Cordes S, Fan X, Jabara I, Zhou Y, Young DJ, Lee BC, Yu KR, Li Y, Toms B, Tunc I, Hong SG, Truitt LL, Klermund J, Andrieux G, Kim MY, Cathomen T, Gill S, Tsai SQ, Dunbar CE. AlJanahi AA, et al. Among authors: klermund j. Mol Ther. 2022 Jan 5;30(1):209-222. doi: 10.1016/j.ymthe.2021.06.016. Epub 2021 Jun 24. Mol Ther. 2022. PMID: 34174439 Free PMC article.
On- and off-target effects of paired CRISPR-Cas nickase in primary human cells.
Klermund J, Rhiel M, Kocher T, Chmielewski KO, Bischof J, Andrieux G, El Gaz M, Hainzl S, Boerries M, Cornu TI, Koller U, Cathomen T. Klermund J, et al. Mol Ther. 2024 Mar 7:S1525-0016(24)00147-3. doi: 10.1016/j.ymthe.2024.03.006. Online ahead of print. Mol Ther. 2024. PMID: 38459694 Free article.
11 results