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Precise excision of HTLV-1 provirus with a designer-recombinase.
Rojo-Romanos T, Karpinski J, Millen S, Beschorner N, Simon F, Paszkowski-Rogacz M, Lansing F, Schneider PM, Sonntag J, Hauber J, Thoma-Kress AK, Buchholz F. Rojo-Romanos T, et al. Among authors: lansing f. Mol Ther. 2023 Jul 5;31(7):2266-2285. doi: 10.1016/j.ymthe.2023.03.014. Epub 2023 Mar 17. Mol Ther. 2023. PMID: 36934299 Free article.
Correction of a Factor VIII genomic inversion with designer-recombinases.
Lansing F, Mukhametzyanova L, Rojo-Romanos T, Iwasawa K, Kimura M, Paszkowski-Rogacz M, Karpinski J, Grass T, Sonntag J, Schneider PM, Günes C, Hoersten J, Schmitt LT, Rodriguez-Muela N, Knöfler R, Takebe T, Buchholz F. Lansing F, et al. Nat Commun. 2022 Jan 20;13(1):422. doi: 10.1038/s41467-022-28080-7. Nat Commun. 2022. PMID: 35058465 Free PMC article.
Quantification of evolved DNA-editing enzymes at scale with DEQSeq.
Schmitt LT, Schneider A, Posorski J, Lansing F, Jelicic M, Jain M, Sayed S, Buchholz F, Sürün D. Schmitt LT, et al. Among authors: lansing f. Genome Biol. 2023 Nov 6;24(1):254. doi: 10.1186/s13059-023-03097-3. Genome Biol. 2023. PMID: 37932818 Free PMC article.
Activation of recombinases at specific DNA loci by zinc-finger domain insertions.
Mukhametzyanova L, Schmitt LT, Torres-Rivera J, Rojo-Romanos T, Lansing F, Paszkowski-Rogacz M, Hollak H, Brux M, Augsburg M, Schneider PM, Buchholz F. Mukhametzyanova L, et al. Among authors: lansing f. Nat Biotechnol. 2024 Jan 31. doi: 10.1038/s41587-023-02121-y. Online ahead of print. Nat Biotechnol. 2024. PMID: 38297187