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Year Number of Results
2020 5
2021 1
2022 3
2023 4
2024 1

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14 results

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Page 1
A cell atlas of human thymic development defines T cell repertoire formation.
Park JE, Botting RA, Domínguez Conde C, Popescu DM, Lavaert M, Kunz DJ, Goh I, Stephenson E, Ragazzini R, Tuck E, Wilbrey-Clark A, Roberts K, Kedlian VR, Ferdinand JR, He X, Webb S, Maunder D, Vandamme N, Mahbubani KT, Polanski K, Mamanova L, Bolt L, Crossland D, de Rita F, Fuller A, Filby A, Reynolds G, Dixon D, Saeb-Parsy K, Lisgo S, Henderson D, Vento-Tormo R, Bayraktar OA, Barker RA, Meyer KB, Saeys Y, Bonfanti P, Behjati S, Clatworthy MR, Taghon T, Haniffa M, Teichmann SA. Park JE, et al. Among authors: lavaert m. Science. 2020 Feb 21;367(6480):eaay3224. doi: 10.1126/science.aay3224. Science. 2020. PMID: 32079746 Free PMC article.
Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function.
Zhang Y, Bailey JT, Xu E, Singh K, Lavaert M, Link VM, D'Souza S, Hafiz A, Cao J, Cao G, Sant'Angelo DB, Sun W, Belkaid Y, Bhandoola A, McGavern DB, Yang Q. Zhang Y, et al. Among authors: lavaert m. Nat Immunol. 2022 Dec;23(12):1714-1725. doi: 10.1038/s41590-022-01349-1. Epub 2022 Nov 21. Nat Immunol. 2022. PMID: 36411380 Free PMC article.
Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage.
Billiet L, De Cock L, Sanchez Sanchez G, Mayer RL, Goetgeluk G, De Munter S, Pille M, Ingels J, Jansen H, Weening K, Pascal E, Raes K, Bonte S, Kerre T, Vandamme N, Seurinck R, Roels J, Lavaert M, Van Nieuwerburgh F, Leclercq G, Taghon T, Impens F, Menten B, Vermijlen D, Vandekerckhove B. Billiet L, et al. Among authors: lavaert m. J Exp Med. 2023 Jun 5;220(6):e20220942. doi: 10.1084/jem.20220942. Epub 2023 Mar 20. J Exp Med. 2023. PMID: 36939517 Free PMC article.
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF.
Liang KL, Roels J, Lavaert M, Putteman T, Boehme L, Tilleman L, Velghe I, Pegoretti V, Van de Walle I, Sontag S, Vandewalle J, Vandekerckhove B, Leclercq G, Van Vlierberghe P, Libert C, Van Nieuwerburgh F, Fischer R, Kontermann RE, Pfizenmaier K, Doody G, Zenke M, Taghon T. Liang KL, et al. Among authors: lavaert m. Nat Immunol. 2023 Mar;24(3):474-486. doi: 10.1038/s41590-022-01417-6. Epub 2023 Jan 26. Nat Immunol. 2023. PMID: 36703005 Free article.
Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development.
Malin J, Martinez-Ruiz GU, Zhao Y, Shissler SC, Cowan JE, Ding Y, Morales-Sanchez A, Ishikawa M, Lavaert M, Das A, Butcher D, Warner AC, Kallarakal M, Chen J, Kedei N, Kelly M, Brinster LR, Allman D, Bhandoola A. Malin J, et al. Among authors: lavaert m. Sci Adv. 2023 Nov 17;9(46):eadg8126. doi: 10.1126/sciadv.adg8126. Epub 2023 Nov 15. Sci Adv. 2023. PMID: 37967174 Free PMC article.
Bone marrow plasma cells require P2RX4 to sense extracellular ATP.
Ishikawa M, Hasanali ZS, Zhao Y, Das A, Lavaert M, Roman CJ, Londregan J, Allman D, Bhandoola A. Ishikawa M, et al. Among authors: lavaert m. Nature. 2024 Feb;626(8001):1102-1107. doi: 10.1038/s41586-024-07047-2. Epub 2024 Feb 14. Nature. 2024. PMID: 38355795 Free PMC article.
T cell development made EZ.
Lavaert M, Bhandoola A. Lavaert M, et al. Cell Stem Cell. 2022 Aug 4;29(8):1155-1156. doi: 10.1016/j.stem.2022.07.003. Cell Stem Cell. 2022. PMID: 35931025 Free article.
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes.
Lavaert M, Liang KL, Vandamme N, Park JE, Roels J, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Vandekerckhove B, Leclercq G, Regev A, Van Vlierberghe P, Guilliams M, Teichmann SA, Saeys Y, Taghon T. Lavaert M, et al. Immunity. 2020 Jun 16;52(6):1088-1104.e6. doi: 10.1016/j.immuni.2020.03.019. Epub 2020 Apr 17. Immunity. 2020. PMID: 32304633 Free article.
Identification and Purification of Human T Cell Precursors.
Van de Walle I, Lambrechts N, Derveeuw A, Lavaert M, Roels J, Taghon T. Van de Walle I, et al. Among authors: lavaert m. Methods Mol Biol. 2023;2580:315-333. doi: 10.1007/978-1-0716-2740-2_20. Methods Mol Biol. 2023. PMID: 36374467
Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development.
Dolens AC, Durinck K, Lavaert M, Van der Meulen J, Velghe I, De Medts J, Weening K, Roels J, De Mulder K, Volders PJ, De Preter K, Kerre T, Vandekerckhove B, Leclercq G, Vandesompele J, Mestdagh P, Van Vlierberghe P, Speleman F, Taghon T. Dolens AC, et al. Among authors: lavaert m. EMBO Rep. 2020 May 6;21(5):e49006. doi: 10.15252/embr.201949006. Epub 2020 Apr 7. EMBO Rep. 2020. PMID: 32255245 Free PMC article.
14 results