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2019 3
2020 1
2021 3
2022 1
2024 0

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Page 1
Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells.
Raveendra-Panickar D, Finlay D, Layng FI, Lambert LJ, Celeridad M, Zhao M, Barbosa K, De Backer LJS, Kwong E, Gosalia P, Rodiles S, Holleran J, Ardecky R, Grotegut S, Olson S, Hutchinson JH, Pasquale EB, Vuori K, Deshpande AJ, Cosford NDP, Tautz L. Raveendra-Panickar D, et al. Among authors: layng fi. J Biol Chem. 2022 Jan;298(1):101477. doi: 10.1016/j.jbc.2021.101477. Epub 2021 Dec 10. J Biol Chem. 2022. PMID: 34896393 Free PMC article.
PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.
Jeung HC, Puentes R, Aleshin A, Indarte M, Correa RG, Bankston LA, Layng FIAL, Ahmed Z, Wistuba I, Yao Y, Duenas DG, Zhang S, Meuillet EJ, Marassi F, Liddington RC, Kirkpatrick L, Powis G. Jeung HC, et al. Among authors: layng fial. Exp Cell Res. 2021 Dec 15;409(2):112930. doi: 10.1016/j.yexcr.2021.112930. Epub 2021 Nov 17. Exp Cell Res. 2021. PMID: 34800542 Free PMC article.
MicroRNA-211 Modulates the DUSP6-ERK5 Signaling Axis to Promote BRAFV600E-Driven Melanoma Growth In Vivo and BRAF/MEK Inhibitor Resistance.
Lee B, Sahoo A, Sawada J, Marchica J, Sahoo S, Layng FIAL, Finlay D, Mazar J, Joshi P, Komatsu M, Vuori K, de Jong PR, Ray A, Perera RJ. Lee B, et al. Among authors: layng fial. J Invest Dermatol. 2021 Feb;141(2):385-394. doi: 10.1016/j.jid.2020.06.038. Epub 2020 Sep 2. J Invest Dermatol. 2021. PMID: 32888955 Free PMC article.
An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors.
Indarte M, Puentes R, Maruggi M, Ihle NT, Grandjean G, Scott M, Ahmed Z, Meuillet EJ, Zang S, Lemos R Jr, Du-Cuny L, Layng FIAL, Correa RG, Bankston LA, Liddington RC, Kirkpatrick L, Powis G. Indarte M, et al. Among authors: layng fial. Cancer Res. 2019 Jun 15;79(12):3100-3111. doi: 10.1158/0008-5472.CAN-18-2372. Epub 2019 Apr 30. Cancer Res. 2019. PMID: 31040156 Free PMC article.
Correction: An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors.
Indarte M, Puentes R, Maruggi M, Ihle NT, Grandjean G, Scott M, Ahmed Z, Meuillet EJ, Zhang S, Lemos R Jr, Du-Cuny L, Layng FIAL, Correa RG, Bankston LA, Liddington RC, Kirkpatrick L, Powis G. Indarte M, et al. Among authors: layng fial. Cancer Res. 2019 Oct 15;79(20):5457. doi: 10.1158/0008-5472.CAN-19-2586. Cancer Res. 2019. PMID: 31615811 No abstract available.